TY - JOUR
T1 - Nanotechnology integration for sars-cov-2 diagnosis and treatment
T2 - An approach to preventing pandemic
AU - Asdaq, Syed Mohammed Basheeruddin
AU - Ikbal, Abu Md Ashif
AU - Sahu, Ram Kumar
AU - Bhattacharjee, Bedanta
AU - Paul, Tirna
AU - Deka, Bhargab
AU - Fattepur, Santosh
AU - Widyowati, Retno
AU - Vijaya, Joshi
AU - Al Mohaini, Mohammed
AU - Alsalman, Abdulkhaliq J.
AU - Imran, Mohd
AU - Nagaraja, Sreeharsha
AU - Nair, Anroop B.
AU - Attimarad, Mahesh
AU - Venugopala, Katharigatta N.
N1 - Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/7
Y1 - 2021/7
N2 - The SARS-CoV-2 outbreak is the COVID-19 disease, which has caused massive health devastation, prompting the World Health Organization to declare a worldwide health emergency. The corona virus infected millions of people worldwide, and many died as a result of a lack of particular medications. The current emergency necessitates extensive therapy in order to stop the spread of the coronavirus. There are various vaccinations available, but no validated COVID-19 treatments. Since its outbreak, many therapeutics have been tested, including the use of repurposed medications, nucleoside inhibitors, protease inhibitors, broad spectrum antivirals, convalescence plasma therapies, immune-modulators, and monoclonal antibodies. However, these approaches have not yielded any outcomes and are mostly used to alleviate symptoms associated with potentially fatal adverse drug reactions. Nanoparticles, on the other hand, may prove to be an effective treatment for COVID-19. They can be designed to boost the efficacy of currently available antiviral medications or to trigger a rapid immune response against COVID-19. In the last decade, there has been significant progress in nanotechnology. This review focuses on the virus’s basic structure, pathogenesis, and current treatment options for COVID-19. This study addresses nanotechnology and its applications in diagnosis, prevention, treatment, and targeted vaccine delivery, laying the groundwork for a successful pandemic fight.
AB - The SARS-CoV-2 outbreak is the COVID-19 disease, which has caused massive health devastation, prompting the World Health Organization to declare a worldwide health emergency. The corona virus infected millions of people worldwide, and many died as a result of a lack of particular medications. The current emergency necessitates extensive therapy in order to stop the spread of the coronavirus. There are various vaccinations available, but no validated COVID-19 treatments. Since its outbreak, many therapeutics have been tested, including the use of repurposed medications, nucleoside inhibitors, protease inhibitors, broad spectrum antivirals, convalescence plasma therapies, immune-modulators, and monoclonal antibodies. However, these approaches have not yielded any outcomes and are mostly used to alleviate symptoms associated with potentially fatal adverse drug reactions. Nanoparticles, on the other hand, may prove to be an effective treatment for COVID-19. They can be designed to boost the efficacy of currently available antiviral medications or to trigger a rapid immune response against COVID-19. In the last decade, there has been significant progress in nanotechnology. This review focuses on the virus’s basic structure, pathogenesis, and current treatment options for COVID-19. This study addresses nanotechnology and its applications in diagnosis, prevention, treatment, and targeted vaccine delivery, laying the groundwork for a successful pandemic fight.
KW - Biosensors
KW - COVID-19
KW - Nanotechnology
KW - Sanitizers
KW - Vaccines
UR - http://www.scopus.com/inward/record.url?scp=85110132007&partnerID=8YFLogxK
U2 - 10.3390/nano11071841
DO - 10.3390/nano11071841
M3 - Review article
AN - SCOPUS:85110132007
SN - 2079-4991
VL - 11
JO - Nanomaterials
JF - Nanomaterials
IS - 7
M1 - 1841
ER -