Stem cells are generally understood as having the ability to self-renew under appropriate conditions and to differentiate into specialized phenotypes. Mesenchymal Stem Cells, in particular can be readily expanded to make a significant number of population doublings within cultures, which can then differentiate into various mesenchymal phenotypes. The use of skin is an appropriate source of cells due to its availability, noninvasive accessibility, as well as its low risk for oncogenesis after transplantation. In this 14 day, in vitro study, the presence of lipid droplets confirmed mesenchymal differentiation into adipocytes and was observed by oil red o staining following 1 week of adipogenic induction.
- Adipogenic differentiation
- Oilred O
- Skin derived mesenchymal stem cells