Multipotency of rabbit (oryctolagus cuniculus) skin-derived mesenchymal stem cells (SMSCs) induced to adipogenic progenitors in VITRO

Deya Karsari; Aristika Dinaryanti; Nora Ertanti; Igo Syaiful Ihsan; Illiyun Illa Renza; Fedik Abdul Rantam

doi:10.35124/bca.2019.19.S2.4755

Multipotency of rabbit (oryctolagus cuniculus) skin-derived mesenchymal stem cells (SMSCs) induced to adipogenic progenitors in VITRO

Deya Karsari, Aristika Dinaryanti, Nora Ertanti, Igo Syaiful Ihsan, Illiyun Illa Renza, Fedik Abdul Rantam, Purwati

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Stem cells are generally understood as having the ability to self-renew under appropriate conditions and to differentiate into specialized phenotypes. Mesenchymal Stem Cells, in particular can be readily expanded to make a significant number of population doublings within cultures, which can then differentiate into various mesenchymal phenotypes. The use of skin is an appropriate source of cells due to its availability, noninvasive accessibility, as well as its low risk for oncogenesis after transplantation. In this 14 day, in vitro study, the presence of lipid droplets confirmed mesenchymal differentiation into adipocytes and was observed by oil red o staining following 1 week of adipogenic induction.

Original language	English
Pages (from-to)	4755-4758
Number of pages	4
Journal	Biochemical and Cellular Archives
DOIs	https://doi.org/10.35124/bca.2019.19.S2.4755
Publication status	Published - 1 Dec 2019

Keywords

Adipocyte
Adipogenic differentiation
Oilred O
Skin derived mesenchymal stem cells
SMSCs

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title = "Multipotency of rabbit (oryctolagus cuniculus) skin-derived mesenchymal stem cells (SMSCs) induced to adipogenic progenitors in VITRO",

abstract = "Stem cells are generally understood as having the ability to self-renew under appropriate conditions and to differentiate into specialized phenotypes. Mesenchymal Stem Cells, in particular can be readily expanded to make a significant number of population doublings within cultures, which can then differentiate into various mesenchymal phenotypes. The use of skin is an appropriate source of cells due to its availability, noninvasive accessibility, as well as its low risk for oncogenesis after transplantation. In this 14 day, in vitro study, the presence of lipid droplets confirmed mesenchymal differentiation into adipocytes and was observed by oil red o staining following 1 week of adipogenic induction.",

keywords = "Adipocyte, Adipogenic differentiation, Oilred O, Skin derived mesenchymal stem cells, SMSCs",

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AU - Karsari, Deya

AU - Dinaryanti, Aristika

AU - Ertanti, Nora

AU - Ihsan, Igo Syaiful

AU - Renza, Illiyun Illa

AU - Rantam, Fedik Abdul

AU - Purwati,

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AB - Stem cells are generally understood as having the ability to self-renew under appropriate conditions and to differentiate into specialized phenotypes. Mesenchymal Stem Cells, in particular can be readily expanded to make a significant number of population doublings within cultures, which can then differentiate into various mesenchymal phenotypes. The use of skin is an appropriate source of cells due to its availability, noninvasive accessibility, as well as its low risk for oncogenesis after transplantation. In this 14 day, in vitro study, the presence of lipid droplets confirmed mesenchymal differentiation into adipocytes and was observed by oil red o staining following 1 week of adipogenic induction.

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KW - Adipogenic differentiation

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Multipotency of rabbit (oryctolagus cuniculus) skin-derived mesenchymal stem cells (SMSCs) induced to adipogenic progenitors in VITRO

Abstract

Keywords

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