Multipotency of rabbit (oryctolagus cuniculus) skin-derived mesenchymal stem cells (SMSCs) induced to adipogenic progenitors in VITRO

Deya Karsari, Aristika Dinaryanti, Nora Ertanti, Igo Syaiful Ihsan, Illiyun Illa Renza, Fedik Abdul Rantam, Purwati

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Stem cells are generally understood as having the ability to self-renew under appropriate conditions and to differentiate into specialized phenotypes. Mesenchymal Stem Cells, in particular can be readily expanded to make a significant number of population doublings within cultures, which can then differentiate into various mesenchymal phenotypes. The use of skin is an appropriate source of cells due to its availability, noninvasive accessibility, as well as its low risk for oncogenesis after transplantation. In this 14 day, in vitro study, the presence of lipid droplets confirmed mesenchymal differentiation into adipocytes and was observed by oil red o staining following 1 week of adipogenic induction.

Original languageEnglish
Pages (from-to)4755-4758
Number of pages4
JournalBiochemical and Cellular Archives
DOIs
Publication statusPublished - 1 Dec 2019

Keywords

  • Adipocyte
  • Adipogenic differentiation
  • Oilred O
  • Skin derived mesenchymal stem cells
  • SMSCs

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