Background: Periodontal ailment is in a way the most frequent disorder that humanity faces. Severe periodontitis, which affects roughly 743 million people globally around the world, is the sixth-grade greatest prevalence (11.2%) of any illness. Hydroxyapatite (HA) is a major element for bone regeneration. Biocompatibility, bioactivity, low degradation, osteoconduction, osteointegration, and osteoinduction are all big benefits of HA. Osteoinduction is a system wherein osteoprogenitor cells are stimulated to turn into osteoblasts, which then start the development of new bone. Purpose: This study provides a complete overview of the history and evolution of the use of HA for various regeneration applications, as well as evolving trends. Conclusion: By using HA as a scaffold for osteoinduction, osteoprogenitor cells are stimulated to form osteoblasts, which subsequently initiate the construction of new bone.

Original languageEnglish
Pages (from-to)591-594
Number of pages4
JournalResearch Journal of Pharmacy and Technology
Issue number2
Publication statusPublished - 2024


  • Bone regeneration
  • Medicine
  • Micro hydroxyapatite
  • Osteoconduction


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