Methyl-3,4-dihydroxybenzoate and 9-10-dihydrophenanthrene-2,4,7-triol two phenolic compounds from Dioscorea alata L. and their antioxidant activity

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Abstract

Two phenolic compounds namely: methyl-3,4-dihydroxybenzoate (1) and 9,10-dihydrophenanthrene-2,4,7-triol (2) had been isolated for the first time from the tuber of Dioscorea alata L. The extraction of two compounds were done by maceration method using methanol as solvent, followed by partition with n-hexane and ethyl acetate. The ethyl acetate extract was separated and purified using various chromatographic techniques yielded pure compounds. The structure of isolated compounds were determined based on spectroscopic data, including UV-Vis, 1D and 2D NMR spectra. Compounds (1), (2) and ascorbic acid as a comparator were evaluated for their antioxidant properties against DPPH, showing their IC50 were 9,41 ± 0,08; 23,52 ± 0,05; and 10,95 ± 0,08 ppm, respectively.

Original languageEnglish
Title of host publication6th International Conference and Workshops on Basic and Applied Sciences
EditorsHewa Y. Abdullah
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735415713
DOIs
Publication statusPublished - 21 Sept 2017
Event6th International Conference and Workshops on Basic and Applied Sciences, ICOWOBAS 2017 - Erbil, Kurdistan, Iraq
Duration: 18 Mar 201719 Mar 2017

Publication series

NameAIP Conference Proceedings
Volume1888
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference6th International Conference and Workshops on Basic and Applied Sciences, ICOWOBAS 2017
Country/TerritoryIraq
CityErbil, Kurdistan
Period18/03/1719/03/17

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