TY - GEN
T1 - Methyl-3,4-dihydroxybenzoate and 9-10-dihydrophenanthrene-2,4,7-triol two phenolic compounds from Dioscorea alata L. and their antioxidant activity
AU - Aminah, N. S.
AU - Yulvia, A.
AU - Tanjung, M.
N1 - Publisher Copyright:
© 2017 Author(s).
PY - 2017/9/21
Y1 - 2017/9/21
N2 - Two phenolic compounds namely: methyl-3,4-dihydroxybenzoate (1) and 9,10-dihydrophenanthrene-2,4,7-triol (2) had been isolated for the first time from the tuber of Dioscorea alata L. The extraction of two compounds were done by maceration method using methanol as solvent, followed by partition with n-hexane and ethyl acetate. The ethyl acetate extract was separated and purified using various chromatographic techniques yielded pure compounds. The structure of isolated compounds were determined based on spectroscopic data, including UV-Vis, 1D and 2D NMR spectra. Compounds (1), (2) and ascorbic acid as a comparator were evaluated for their antioxidant properties against DPPH, showing their IC50 were 9,41 ± 0,08; 23,52 ± 0,05; and 10,95 ± 0,08 ppm, respectively.
AB - Two phenolic compounds namely: methyl-3,4-dihydroxybenzoate (1) and 9,10-dihydrophenanthrene-2,4,7-triol (2) had been isolated for the first time from the tuber of Dioscorea alata L. The extraction of two compounds were done by maceration method using methanol as solvent, followed by partition with n-hexane and ethyl acetate. The ethyl acetate extract was separated and purified using various chromatographic techniques yielded pure compounds. The structure of isolated compounds were determined based on spectroscopic data, including UV-Vis, 1D and 2D NMR spectra. Compounds (1), (2) and ascorbic acid as a comparator were evaluated for their antioxidant properties against DPPH, showing their IC50 were 9,41 ± 0,08; 23,52 ± 0,05; and 10,95 ± 0,08 ppm, respectively.
UR - http://www.scopus.com/inward/record.url?scp=85030774387&partnerID=8YFLogxK
U2 - 10.1063/1.5004327
DO - 10.1063/1.5004327
M3 - Conference contribution
AN - SCOPUS:85030774387
T3 - AIP Conference Proceedings
BT - 6th International Conference and Workshops on Basic and Applied Sciences
A2 - Abdullah, Hewa Y.
PB - American Institute of Physics Inc.
T2 - 6th International Conference and Workshops on Basic and Applied Sciences, ICOWOBAS 2017
Y2 - 18 March 2017 through 19 March 2017
ER -