TY - JOUR
T1 - Mesucalophylloidin, a new isoprenylated 4-phenylcoumarin from Mesua calophylloides (Ridl.) Kosterm
AU - Tanjung, Mulyadi
AU - Rachmadiarti, Fida
AU - Saputri, Ratih Dewi
AU - Tjahjandarie, Tjitjik Srie
N1 - Publisher Copyright:
© 2017 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2018/5/3
Y1 - 2018/5/3
N2 - A new isoprenylated 4-phenylcoumarin derivative, mesucalophylloidin (1) along with three known compounds, mammea A/BA cyclo F (2), calolongic acid (3) and isocalolongic acid (4) were isolated from the stem bark of Mesua calophylloides (Ridl.) Kosterm. Structures of all the compounds were elucidated using extensive spectroscopic methods, including UV, IR, HRESIMS, 1D and 2D NMR. Compounds 1–4 were evaluated for their cytotoxicity against P-388 cells, showing that compound 1 gave moderate activity with IC50 6.26 μg/mL.
AB - A new isoprenylated 4-phenylcoumarin derivative, mesucalophylloidin (1) along with three known compounds, mammea A/BA cyclo F (2), calolongic acid (3) and isocalolongic acid (4) were isolated from the stem bark of Mesua calophylloides (Ridl.) Kosterm. Structures of all the compounds were elucidated using extensive spectroscopic methods, including UV, IR, HRESIMS, 1D and 2D NMR. Compounds 1–4 were evaluated for their cytotoxicity against P-388 cells, showing that compound 1 gave moderate activity with IC50 6.26 μg/mL.
KW - Mesua calophylloides
KW - Mesucalophylloidin
KW - P-388 cell
KW - isoprenylated 4-phenylcoumarin
UR - http://www.scopus.com/inward/record.url?scp=85030163058&partnerID=8YFLogxK
U2 - 10.1080/14786419.2017.1378215
DO - 10.1080/14786419.2017.1378215
M3 - Article
C2 - 28950715
AN - SCOPUS:85030163058
SN - 1478-6419
VL - 32
SP - 1062
EP - 1067
JO - Natural Product Research
JF - Natural Product Research
IS - 9
ER -
