TY - JOUR
T1 - Meliglabrin, a new flavonol derivative from the leaves of melicope glabra (Blume) T.G. Hartley
AU - Saputri, Ratih Dewi
AU - Tjahjandarie, Tjitjik Srie
AU - Tanjung, Mulyadi
N1 - Publisher Copyright:
© 2018, Korean Society of Pharmacognosy. All rights reserved.
PY - 2018
Y1 - 2018
N2 - A new flavonol derivative, meliglabrin (1) along with three known flavonols, ternatin (2), meliternatin (3), and 5,4’-dihydroxy-3,7,3’-trimethoxyflavon (4) were isolated from the leaves of Melicope glabra (Blume) T.G. Hartley. Their structures were determined using extensive spectroscopic methods, including UV, IR, HRESIMS, 1D and 2D NMR. Compounds 1-4 were evaluated for their cytotoxicity against murine leukemia P-388 cells, compound 4 showed moderate activity.
AB - A new flavonol derivative, meliglabrin (1) along with three known flavonols, ternatin (2), meliternatin (3), and 5,4’-dihydroxy-3,7,3’-trimethoxyflavon (4) were isolated from the leaves of Melicope glabra (Blume) T.G. Hartley. Their structures were determined using extensive spectroscopic methods, including UV, IR, HRESIMS, 1D and 2D NMR. Compounds 1-4 were evaluated for their cytotoxicity against murine leukemia P-388 cells, compound 4 showed moderate activity.
KW - Flavonol
KW - Melicope glabra
KW - Meliglabrin
KW - P-388 cells
UR - http://www.scopus.com/inward/record.url?scp=85058149439&partnerID=8YFLogxK
U2 - 10.20307/nps.2018.24.3.155
DO - 10.20307/nps.2018.24.3.155
M3 - Article
AN - SCOPUS:85058149439
SN - 1226-3907
VL - 24
SP - 155
EP - 158
JO - Natural Product Sciences
JF - Natural Product Sciences
IS - 3
ER -
