Management and outcomes following emergency surgery for traumatic brain injury – A multi-centre, international, prospective cohort study (the Global Neurotrauma Outcomes Study)

David Clark, Alexis Joannides, Omar Ibrahim Abdallah, Amos Olufemi Adeleye, Abdul Hafid Bajamal, Tom Bashford, Arnold Bhebhe, Hagos Biluts, Natalia Budohoska, Karol Budohoski, Iype Cherian, Niklas Marklund, Rocio Fernandez Mendez, Tony Figaji, Deepak Kumar Gupta, Corrado Iaccarino, Ali Ilunga, Mathew Joseph, Tariq Khan, Tsegazeab LaekeVicknes Waran, Kee Park, Gail Rosseau, Andres Rubiano, Youssuf Saleh, Hamisi K. Shabani, Brandon Smith, Kachinga Sichizya, Manoj Tewari, Abenezer Tirsit, Myat Thu, Manjul Tripathi, Rikin Trivedi, Sofia Villar, Indira Devi Bhagavatula, Franco Servadei, David Menon, Angelos Kolias, Peter Hutchinson

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

Introduction: Traumatic brain injury (TBI) accounts for a significant amount of death and disability worldwide and the majority of this burden affects individuals in low-and-middle income countries. Despite this, considerable geographical differences have been reported in the care of TBI patients. On this background, we aim to provide a comprehensive international picture of the epidemiological characteristics, management and outcomes of patients undergoing emergency surgery for traumatic brain injury (TBI) worldwide. Methods and analysis: The Global Neurotrauma Outcomes Study (GNOS) is a multi-centre, international, prospective observational cohort study. Any unit performing emergency surgery for TBI worldwide will be eligible to participate. All TBI patients who receive emergency surgery in any given consecutive 30-day period beginning between 1st of November 2018 and 31st of December 2019 in a given participating unit will be included. Data will be collected via a secure online platform in anonymised form. The primary outcome measures for the study will be 14-day mortality (or survival to hospital discharge, whichever comes first). Final day of data collection for the primary outcome measure is February 13th. Secondary outcome measures include return to theatre and surgical site infection. Ethics and dissemination: This project will not affect clinical practice and has been classified as clinical audit following research ethics review. Access to source data will be made available to collaborators through national or international anonymised datasets on request and after review of the scientific validity of the proposed analysis by the central study team.

Original languageEnglish
Pages (from-to)1-7
Number of pages7
JournalInternational Journal of Surgery Protocols
Volume20
DOIs
Publication statusPublished - 2020

Keywords

  • Brain injuries
  • Epidemiology
  • Global health
  • Injuries
  • Neurosurgery
  • Traumatic

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