TY - JOUR
T1 - Magnesium intoxication in women with preeclampsia with severe features treated with magnesium sulfate
AU - Akbar, Muhammad Ilham Aldika
AU - Yoseph, Daniel
AU - Aditiawarman,
AU - Bachnas, Muhammad Adrianes
AU - Dachlan, Erry Gumilar
AU - Dekker, Gustaaf Albert
AU - Ernawati,
N1 - Funding Information:
We thank Prof. Dr. Hendy Hendarto dr. SpOG(K) as the head of department who supported and gave permission to perform this study; we thank all staff in Department Obstetrics & Gynecology Faculty of Medicine Universitas Airlangga - RSUD Dr. Soetomo - RS Universitas Airlangga for their genuine support for this study; we thank our resident in training and the research team for their hard work in collecting data in this study; and we would like to thank all the patients who were involved in this study, without their participation the study could never be completed.
Publisher Copyright:
© 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2020/7/2
Y1 - 2020/7/2
N2 - Objective: To evaluate the maternal-neonatal outcome in magnesium (Mg)-intoxicated women with preeclampsia with severe features (PESF) treated with magnesium sulfate (MgSO4). Methods: A total of 19 Mg intoxicated PESF women (cases) were compared with 166 PESF women without signs of intoxication (controls). Results: Mg serum levels of cases was higher compared to control group (12.36 ± 3.54 mg/dl versus 2.69 ± 0.83 mg/dl). 3 women died and 3 had major maternal morbidity in cases group compared with zero in the control group (P = 0.009). Mg intoxication was also significantly associated with perinatal deaths and low Apgar scores at 1 and 5 minutes. Conclusion: Mg intoxication is associated with a increased risk of maternal and perinatal mortality and morbidity.
AB - Objective: To evaluate the maternal-neonatal outcome in magnesium (Mg)-intoxicated women with preeclampsia with severe features (PESF) treated with magnesium sulfate (MgSO4). Methods: A total of 19 Mg intoxicated PESF women (cases) were compared with 166 PESF women without signs of intoxication (controls). Results: Mg serum levels of cases was higher compared to control group (12.36 ± 3.54 mg/dl versus 2.69 ± 0.83 mg/dl). 3 women died and 3 had major maternal morbidity in cases group compared with zero in the control group (P = 0.009). Mg intoxication was also significantly associated with perinatal deaths and low Apgar scores at 1 and 5 minutes. Conclusion: Mg intoxication is associated with a increased risk of maternal and perinatal mortality and morbidity.
KW - Magnesium intoxication
KW - hypermagnesemia
KW - magnesium sulfate
KW - preeclampsia with severe features
UR - http://www.scopus.com/inward/record.url?scp=85085892802&partnerID=8YFLogxK
U2 - 10.1080/10641955.2020.1754851
DO - 10.1080/10641955.2020.1754851
M3 - Article
C2 - 32336169
AN - SCOPUS:85085892802
SN - 1064-1955
VL - 39
SP - 221
EP - 227
JO - Hypertension in Pregnancy
JF - Hypertension in Pregnancy
IS - 3
ER -