Macrophage analysis of the combination of moringa leaf extract and DFDBBX in Cavia cobaya tooth extraction sockets

Post-extraction alveolar bone resorption can be minimized, one method of achieving this being socket preservation. A combination of Moringa leaf extract and DFDBBX constitutes a potential anti-inflammatory ingredient. The aim of this study was to determine the inductive role of a combination of Moringa leaf extract and DFDBBX in alveolar bone extraction sockets with regard to macrophages in Cavia cobaya. 56 Cavia cobaya, whose lower left incisors had been extracted were divided into four groups whose extraction sockets were treated with the following substances: (1) control group: PEG, (2) group 2: DFDBBX, (3) group 3: Moringa leaf extract and (4) group 4: a combination of DFDBBX and Moringa leaf extract. Examination was conducted on days 7 and 30 after which the Cavia cobaya were sacrificed and the macrophage cells counted by means of hematoxilin eosin (HE) staining technique. The resulting data was subjected to a One-Way Anova test. The number of macrophages in each group demonstrated a significant difference. The highest number of macrophages was present in the combination of Moringa leaf extract and DFDBBX in the treatment group on the 7_th and 30th days. In all groups, the number of macrophages after 30 days of treatment was lower than after 7 days. Administering a combination of Moringa leaf extract and DFDBBX is effective in increasing the number of macrophages in extraction sockets of Cavia cobaya.