Macasiamenene v, a new stilbenoid from the leaves of macaranga inermis

Muhammad Fajar Aldin; Tjitjik Srie Tjahjandarie; Ratih Dewi Saputri; Mulyadi Tanjung

doi:10.20307/nps.2021.27.1.45

Macasiamenene v, a new stilbenoid from the leaves of macaranga inermis

Muhammad Fajar Aldin, Tjitjik Srie Tjahjandarie, Ratih Dewi Saputri, Mulyadi Tanjung

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

One new compound, macasiamenene V (1), and two known stilbenes (2-3) were isolated from Macaranga inermis Pax & K.Hoffm leaves. The structure of 1 was fully assigned based on the information on high-resolution MS and (1D, 2D) NMR spectra. The cytotoxic of compounds 1-3 was evaluated against 4T1 and HeLa cells. Compounds 2-3 showed high activity against HeLa cells with an IC₅₀ value of 1.09 and 0.88 μg/mL, respectively.

Original language	English
Pages (from-to)	45-48
Number of pages	4
Journal	Natural Product Sciences
Volume	27
Issue number	1
DOIs	https://doi.org/10.20307/nps.2021.27.1.45
Publication status	Published - 2021

Keywords

-Macasiamenene V
Cytotoxicity
Macaranga inermis
Stilbenoid

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10.20307/nps.2021.27.1.45

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abstract = "One new compound, macasiamenene V (1), and two known stilbenes (2-3) were isolated from Macaranga inermis Pax & K.Hoffm leaves. The structure of 1 was fully assigned based on the information on high-resolution MS and (1D, 2D) NMR spectra. The cytotoxic of compounds 1-3 was evaluated against 4T1 and HeLa cells. Compounds 2-3 showed high activity against HeLa cells with an IC50 value of 1.09 and 0.88 μg/mL, respectively.",

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AU - Saputri, Ratih Dewi

AU - Tanjung, Mulyadi

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PY - 2021

Y1 - 2021

N2 - One new compound, macasiamenene V (1), and two known stilbenes (2-3) were isolated from Macaranga inermis Pax & K.Hoffm leaves. The structure of 1 was fully assigned based on the information on high-resolution MS and (1D, 2D) NMR spectra. The cytotoxic of compounds 1-3 was evaluated against 4T1 and HeLa cells. Compounds 2-3 showed high activity against HeLa cells with an IC50 value of 1.09 and 0.88 μg/mL, respectively.

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Macasiamenene v, a new stilbenoid from the leaves of macaranga inermis

Abstract

Keywords

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