Wound infection of the skin is mainly due to surgery, trauma and insect bites on the mucosa or surface of the skin. The most common bacterial cause of skin infections is Staphylococcus aureus. Many antibiotics used for healing wound infections due to pathogenic bacteria become resistant. The purpose of this study was to determine the ability and optimum dose of lime (Citrus aurantifolia) peel extract in inhibiting the growth of Staphylococcus aureus. The method used in this study was laboratory experiments, using completely randomized design with seven treatments and three replications. Variations in the doses used were 20%, 40%, 60%, 80% and 100%. Kruskal Wallis statistical test produced a significance value of 0.005<α=0.05, indicating that the treatment of lime peel extract had significant effect on the growth of Staphylococcus aureus. The test was continued by Mann Whitney test which produced a significance value of 0.037<α=0.05, indicating significant difference between treatments in each dose. The optimum dose of lime peel extract which can inhibit the growth of Staphylococcus aureus in the sensitive category is 80%.
- Lime (Citrus aurantifolia) peel
- Staphylococcus aureus
- Wound skin infection