Lecythomycin, a new macrolactone glycoside from the endophytic fungus Lecythophora sp.

Noor Erma Sugijanto; Arnulf Diesel; Mostafa Rateb; Alexander Pretsch; Selma Gogalic; Noor Cholies Zaini; Rainer Ebel; Gunawan Indrayanto

doi:10.1177/1934578x1100600521

Lecythomycin, a new macrolactone glycoside from the endophytic fungus Lecythophora sp.

Noor Erma Sugijanto, Arnulf Diesel, Mostafa Rateb, Alexander Pretsch, Selma Gogalic, Noor Cholies Zaini, Rainer Ebel, Gunawan Indrayanto

Faculty of Pharmacy

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

A new macrolactone glycoside, lecythomycin (1), 23-methyl-3-(1-O-mannosyl)- oxacyclotetracosan-1-one, was isolated from the endophytic fungus Lecythophora sp. (code 30.1), an endopyte of the Indonesian plant Alyxia reinwardtii. The structure of 1 was elucidated on the basis of NMR spectroscopic and mass spectrometric data. The isolated compound displayed antifungal activity against strains of Aspergillus fumigatus and Candida kruzei at minimal inhibitory concentrations (MIC) of 62.5-125 μg/mL.

Original language	English
Pages (from-to)	677-678
Number of pages	2
Journal	Natural Product Communications
Volume	6
Issue number	5
DOIs	https://doi.org/10.1177/1934578x1100600521
Publication status	Published - May 2011

Keywords

Alyxia reinwardtii
Endophytic fungus
Lecythomycin
Lecythophora sp
Macrolactone glycoside

Access to Document

10.1177/1934578x1100600521

Cite this

@article{41b32814c3fb42d1a67129fefb3a66ec,

title = "Lecythomycin, a new macrolactone glycoside from the endophytic fungus Lecythophora sp.",

abstract = "A new macrolactone glycoside, lecythomycin (1), 23-methyl-3-(1-O-mannosyl)- oxacyclotetracosan-1-one, was isolated from the endophytic fungus Lecythophora sp. (code 30.1), an endopyte of the Indonesian plant Alyxia reinwardtii. The structure of 1 was elucidated on the basis of NMR spectroscopic and mass spectrometric data. The isolated compound displayed antifungal activity against strains of Aspergillus fumigatus and Candida kruzei at minimal inhibitory concentrations (MIC) of 62.5-125 μg/mL.",

keywords = "Alyxia reinwardtii, Endophytic fungus, Lecythomycin, Lecythophora sp, Macrolactone glycoside",

author = "Sugijanto, {Noor Erma} and Arnulf Diesel and Mostafa Rateb and Alexander Pretsch and Selma Gogalic and Zaini, {Noor Cholies} and Rainer Ebel and Gunawan Indrayanto",

year = "2011",

month = may,

doi = "10.1177/1934578x1100600521",

language = "English",

volume = "6",

pages = "677--678",

journal = "Natural Product Communications",

issn = "1934-578X",

publisher = "SAGE Publications Inc.",

number = "5",

}

TY - JOUR

T1 - Lecythomycin, a new macrolactone glycoside from the endophytic fungus Lecythophora sp.

AU - Sugijanto, Noor Erma

AU - Diesel, Arnulf

AU - Rateb, Mostafa

AU - Pretsch, Alexander

AU - Gogalic, Selma

AU - Zaini, Noor Cholies

AU - Ebel, Rainer

AU - Indrayanto, Gunawan

PY - 2011/5

Y1 - 2011/5

N2 - A new macrolactone glycoside, lecythomycin (1), 23-methyl-3-(1-O-mannosyl)- oxacyclotetracosan-1-one, was isolated from the endophytic fungus Lecythophora sp. (code 30.1), an endopyte of the Indonesian plant Alyxia reinwardtii. The structure of 1 was elucidated on the basis of NMR spectroscopic and mass spectrometric data. The isolated compound displayed antifungal activity against strains of Aspergillus fumigatus and Candida kruzei at minimal inhibitory concentrations (MIC) of 62.5-125 μg/mL.

AB - A new macrolactone glycoside, lecythomycin (1), 23-methyl-3-(1-O-mannosyl)- oxacyclotetracosan-1-one, was isolated from the endophytic fungus Lecythophora sp. (code 30.1), an endopyte of the Indonesian plant Alyxia reinwardtii. The structure of 1 was elucidated on the basis of NMR spectroscopic and mass spectrometric data. The isolated compound displayed antifungal activity against strains of Aspergillus fumigatus and Candida kruzei at minimal inhibitory concentrations (MIC) of 62.5-125 μg/mL.

KW - Alyxia reinwardtii

KW - Endophytic fungus

KW - Lecythomycin

KW - Lecythophora sp

KW - Macrolactone glycoside

UR - http://www.scopus.com/inward/record.url?scp=79955843121&partnerID=8YFLogxK

U2 - 10.1177/1934578x1100600521

DO - 10.1177/1934578x1100600521

M3 - Article

C2 - 21615031

AN - SCOPUS:79955843121

SN - 1934-578X

VL - 6

SP - 677

EP - 678

JO - Natural Product Communications

JF - Natural Product Communications

IS - 5

ER -

Lecythomycin, a new macrolactone glycoside from the endophytic fungus Lecythophora sp.

Abstract

Keywords

Access to Document

Fingerprint

Cite this