Protective effects of acehnese traditionally fermented coconut oil (Pliek U Oil) and its residue (Pliek U) in ointment against UV light exposure: Studies on male wistar rat skin (Rattus novergicus)

Nanda Earlia, Mikyal Bulqiah, Muslem Muslem, Taufiq Karma, Rivansyah Suhendra, Aga Maulana, Mohamad Amin, Novi Reandy Sasmita, Ghazi Mauer Idroes, Crs Prakoeswa, Eko Suhartono, Khairan Khairan, Rinaldi Idroes

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

A protective effect of Acehnese traditionally fermented coconut oil (Pliek U oil) and its residue (Pliek U) have been studied against UVB radiation. The research was performed by preparing the active ingredient in ointment formulation and protective test in male Wistar rat skin (Rattus novergicus). Four different extraction methods were done to produce four active ingredients, that are Pliek U oil (PUO), ethanolic Pliek U oil extract (EPUOE), ethanolic Pliek U extract (EPUE), and ethanolic hexane residue Pliek U extract (EHRPUE). The protective effect was determined based on the erythema index (EI), melanin index (MI), and level of protein oxidation parameters. The protective level from each active ingredient was studied by PCA analysis. The result showed that the active ingredient could inhibit the redness and protein oxidation in skin tissue. PCA results show that concentration (20 v. 40%) does not affect the protection level of the active ingredients of Pliek U oil, but it does affect the one of Pliek U. Therefore, these active ingredients are potential for sunscreen application.

Original languageEnglish
Pages (from-to)1285-1295
Number of pages11
JournalSains Malaysiana
Volume50
Issue number5
DOIs
Publication statusPublished - May 2021
Externally publishedYes

Keywords

  • Erythema index
  • Light exposure
  • Melanin index
  • PCA analysis
  • Pliek U

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