@article{5c38de67d01f4ca79c0e08ddf2a1a106,
title = "Isolation of cytotoxic sesquiterpenes from Curcuma comosa and characterization of their structures",
abstract = "Three quaiane-type sesquiterpenes named curcumenol (1), zedoarondiol (2), and (1S,4S,5S,10R)-isozedoarondiol (3) were isolated from the rhizomes of Curcuma comosa. Their structures were elucidated on the basis of extensive spectroscopic analysis. The cytotoxic activities of all isolated compounds were tested by MTT assay. Compounds 2 and 3 showed the most potent activities against T47D cell line with IC50 values 12.13 and 10.93 μg/mL, respectively.",
keywords = "Curcuma comosa, MTT assay, Quaiane-type sesquiterpenes, Zingiberaceae",
author = "{Win Tun}, {Khun Nay} and Aminah, {Nanik Siti} and Kristanti, {Alfinda Novi} and Rico Ramadhan and Yoshiaki Takaya and Aung, {Hnin Thanda}",
note = "Funding Information: This work was supported by the Ailangga Development Scholarship (ADS) and “RISET MANDAT GRANT” of Universitas Airlangga, Surabaya, Indonesia. Funding Information: This work was supported by the Ailangga Development Scholarship (ADS) and ?RISET MANDAT GRANT? of Universitas Airlangga, Surabaya, Indonesia. Publisher Copyright: {\textcopyright} 2019 Scientific Publishers. All rights reserved.",
year = "2019",
month = dec,
language = "English",
volume = "96",
pages = "1513--1517",
journal = "Journal of the Indian Chemical Society",
issn = "0019-4522",
publisher = "Elsevier BV",
number = "12",
}