Irisin serum increasing pattern is higher at moderate-intensity continuous exercise than at moderate-intensity interval exercise in obese females

Lifestyle, unhealthy eating patterns, and low physical activity become trigger factors of obesity. Therefore, lifestyle modification with an exercise-based nonpharmacological approach is one of the strategies for combat obesity. This study aims to analyse the response of moderate-intensity interval and continuous exercise to irisin level increasing pattern on the obese female. A total of 21 obese females were enrolled in this study and given moderate-intensity interval exercise (MIIE) and moderate-intensity continuous exercise (MICE). ELISA was used to quantify the serum level of irisin in all samples. Statistical analysis was performed using one way-ANOVA and Tukey’s honestly significant difference (HSD) post hoc test. Mean irisin levels of pre-exercise at control (CON), MIIE, and MICE were 3.26±1.28l, 3.44±0.56 and 3.89±1.08 ng/ml, respectively (P=0.519). The mean irisin level of 10 min post-exercise was 2.99±0.86 ng/ml at CON, 4.82±1.01 ng/ml at MIIE, and 5.99±1.27 ng/ml at MICE (P=0.000). The mean irisin levels of 6 h post-exercise were 3.04±0.60, 4.56±0.87, and 5.73±1.02 ng/ml at CON, MIIE, and MICE, respectively (P=0.000). The mean irisin level of 24 h post-exercise was 3.04±0.91 ng/ml at CON, 4.64±0.69 ng/ml at MIIE, and 5.69±1.53 ng/ml at MICE (P=0.002). We conclude that the post-exercise serum irisin level increased in both MICE and MIIE subjects, and the post-exercise serum irisin level maintained higher in the MICE than in the MIIE in the obese female subjects.