Interleukin-6 as immune system and inflammation biomarker on the response of basic pencak silat exercise in perguruan pencak silat perisai diri, bojonegoro

BACKGROUND: Pencak Silat is a self-defense exercise originated from Indonesia and categorized as a high-intensity exercise. AIM: This research was intended to identify the acute response of Pencak Silat basic exercise toward interleukin-6 (IL-6) as an immune system biomarker on students of Perguruan Pencak Silat Perisai Diri Tulungrejo, Bojonegoro. METHODS: A number of 26 students (10 boys and 16 girls) of Perguruan Pencak Silat Tulungrejo, Bojonegoro, were participated in this study. The students did the 2 h Perguruan Pencak Silat Perisai Diri, Bojonegoro, training program with 75–85% intensity. The IL-6 serum was measured using ELISA method. RESULTS: The result of this study showed that the IL-6 serum level in post-2 (12 h after training) (6.2981 pg/mL) was higher compared with the IL-6 serum level in post-1 (shortly after training) (6.11981 pg/mL) and before training (4.5146 pg/mL). The result also showed that there was a significant difference of IL-6 levels between pre-training and after training. CONCLUSION: This study concluded that the basic exercise performed by the new students of Perguruan Pencak Silat Perisai Diri increased IL-6 serum level.