Interleukin-28B polymorphisms and response of chronic hepatitis C patients from Indonesia to pegylated interferon/ribavirin treatment

J. Juniastuti, Bogi P. Wibowo, I. D.N. Wibawa, Takako Utsumi, Syifa Mustika, Mochamad Amin, Rury M. Wahyuni, Hendra Kurniawan, Agus Hendrayana, Poernomo B. Setiawan, Laura N. Yamani, S. Soetjipto, Yoshihiko Yano, Hak Hotta, Yoshitake Hayashi, Maria I. Lusida

Research output: Contribution to journalArticlepeer-review

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Abstract

This study demonstrated that Indonesian patients with chronic hepatitis C (mostly ethnic Java people) mostly were infected with hepatitis C virus (HCV) genotype 1; however, they carried mainly the major genotypes of interleukin 28B (IL-28B) single nucleotide polymorphisms (SNPs) (rs12979860 CC, rs11881222 TT, rs8103142 AA, and rs8099917 TT), and they mostly achieved sustained virological responses to pegylated interferon/ribavirin treatment.

Original languageEnglish
Pages (from-to)2193-2195
Number of pages3
JournalJournal of Clinical Microbiology
Volume52
Issue number6
DOIs
Publication statusPublished - Jun 2014

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