Indonesian propolis: Chemical composition, biological activity and botanical origin

Boryana Trusheva, Milena Popova, Eko Budi Koendhori, Iva Tsvetkova, Christo Naydenski, Vassya Bankova

Research output: Contribution to journalArticlepeer-review

89 Citations (Scopus)

Abstract

From a biologically active extract of Indonesian propolis from East Java, 11 compounds were isolated and identified: four alk(en)ylresorcinols (obtained as an inseparable mixture) (1-4) were isolated for the first time from propolis, along with four prenylflavanones (6-9) and three cycloartane-type triterpenes (5, 10 and 11). The structures of the components were elucidated based on their spectral properties. All prenylflavanones demonstrated significant radical scavenging activity against diphenylpicrylhydrazyl radicals, and compound 6 showed significant antibacterial activity against Staphylococcus aureus. For the first time Macaranga tanarius L. and Mangifera indica L. are shown as plant sources of Indonesian propolis.

Original languageEnglish
Pages (from-to)606-613
Number of pages8
JournalNatural Product Research
Volume25
Issue number6
DOIs
Publication statusPublished - Mar 2011

Keywords

  • Macaranga tanarius
  • Mangifera indica
  • alk(en)ylresorcinols
  • cycloartane triterpenes
  • prenylflavanones
  • propolis

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