TY - JOUR
T1 - Indonesian female with bilateral chylothorax and mediastinal non-Hodgkin lymphoma
T2 - A case report
AU - Wijaya, Sisilia Yolanda
AU - Koesoemoprodjo, Winariani
N1 - Publisher Copyright:
© 2022 The Authors
PY - 2023/1
Y1 - 2023/1
N2 - Background: Bilateral chylothorax is leakage and accumulation of lymph fluid in the pleural space on both sides of the lung and in non-traumatic cases, caused mainly by lymphoma. Case presentation: An Indonesian female, 34 years old, complained of short breath, cough, and swelling in several areas (neck, breast, and hands). Chest X-ray and thorax CT scan showed the anterior mediastinal mass and bilateral pleural effusion. Pleural fluid from both hemithorax was yellow and turbid but odorless. Aerobic culture and cytology of pleural fluid were negative. Triglyceride (TG) of both pleural fluids was >110 mg/dL with the ratio of cholesterol/triglyceride of pleural fluid <1 supporting chylothorax. The core biopsy analysis was negative. Non-Hodgkin lymphoma was established by open thoracotomy biopsy and immunochemistry examination. Chylothorax prognosis was an improvement which was reduced after chest tube insertion. On the outpatient, the patient plans chemotherapy with R CHOP regimen (Rituximab + Cyclophosphamide, prednisone, doxorubicin, and vincristine). Discussion: Malignancy is the primary cause of non-traumatic chylothorax and thoracotomy is used to repair the thoracic duct. Conclusion: Bilateral chylothorax and non-Hodgkin lymphoma were confirmed based on pleural fluid analysis, thoracotomy open biopsy, and immunochemistry examination.
AB - Background: Bilateral chylothorax is leakage and accumulation of lymph fluid in the pleural space on both sides of the lung and in non-traumatic cases, caused mainly by lymphoma. Case presentation: An Indonesian female, 34 years old, complained of short breath, cough, and swelling in several areas (neck, breast, and hands). Chest X-ray and thorax CT scan showed the anterior mediastinal mass and bilateral pleural effusion. Pleural fluid from both hemithorax was yellow and turbid but odorless. Aerobic culture and cytology of pleural fluid were negative. Triglyceride (TG) of both pleural fluids was >110 mg/dL with the ratio of cholesterol/triglyceride of pleural fluid <1 supporting chylothorax. The core biopsy analysis was negative. Non-Hodgkin lymphoma was established by open thoracotomy biopsy and immunochemistry examination. Chylothorax prognosis was an improvement which was reduced after chest tube insertion. On the outpatient, the patient plans chemotherapy with R CHOP regimen (Rituximab + Cyclophosphamide, prednisone, doxorubicin, and vincristine). Discussion: Malignancy is the primary cause of non-traumatic chylothorax and thoracotomy is used to repair the thoracic duct. Conclusion: Bilateral chylothorax and non-Hodgkin lymphoma were confirmed based on pleural fluid analysis, thoracotomy open biopsy, and immunochemistry examination.
KW - Bilateral chylothorax
KW - Mediastinal
KW - Non-Hodgkin lymphoma
KW - cancer
UR - http://www.scopus.com/inward/record.url?scp=85143121792&partnerID=8YFLogxK
U2 - 10.1016/j.ijscr.2022.107827
DO - 10.1016/j.ijscr.2022.107827
M3 - Article
AN - SCOPUS:85143121792
SN - 2210-2612
VL - 102
JO - International Journal of Surgery Case Reports
JF - International Journal of Surgery Case Reports
M1 - 107827
ER -