Imprinted zeolite modified carbon paste electrode as a selective potentiometric sensor for blood glucose

Miratul Khasanah, Alfa Akustia Widati, Usreg Sri Handajani, Masfah Raudlotus Shofiyyah, Sabrina Aulia Rakhma, Herwin Predianto

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

3 Citations (Scopus)

Abstract

Imprinted zeolite modified carbon paste electrode as a potentiometric sensor for glucose analysis in blood serum sample has been developed. In this study, the type of used zeolite was TS-1. Imprinted zeolite (IZ) was synthesized with mole ratio of glucose/Si of 0.0306. The modified electrode prepared by mixing activated carbon, imprinted zeolite, and paraffin granule with mass ratio 9:4:7 from the measurement in range of 10-5 - 10-2 M is with Nernst factor of 28.6 mV/decade, and the detection limit of 4.79 x 10-5 M. The electrode was able to respond the glucose molecules in solution quickly (<30 s), stable for more than 9 weeks (130 times usage) and selective to glucose molecules. The urea, uric acid, and creatine with various concentrations did not interfere to glucose analysis by potentiometry using the electrode. Applying of the electrode for glucose analysis in spiked blood serum samples showed that it had recovery of 91.73±3.48% (n=5), while its accuracy against spectrophotometry method as commonly used method in medical field was 90.58±4.65% (n=5). Based on its performance, potentiometry using the imprinted zeolite modified carbon paste electrode is recommended as an alternative method for routine blood glucose analysis in the medical field.

Original languageEnglish
Title of host publication14th Joint Conference on Chemistry 2019
EditorsFitria Rahmawati, Teguh Endah Saraswati, Khoirina Dwi Nugrahaningtyas, Soerya Dewi Marliyana, Triana Kusumaningsih
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735419964
DOIs
Publication statusPublished - 2 Jun 2020
Event14th Joint Conference on Chemistry 2019, JCC 2019 - Surakarta, Indonesia
Duration: 10 Sep 201911 Sep 2019

Publication series

NameAIP Conference Proceedings
Volume2237
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference14th Joint Conference on Chemistry 2019, JCC 2019
Country/TerritoryIndonesia
CitySurakarta
Period10/09/1911/09/19

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