Impacts of dynamic degradation on the morphological and mechanical characterisation of porous magnesium scaffold

Amir Putra Md Saad, Akbar Teguh Prakoso, M. A. Sulong, Hasan Basri, Dian Agustin Wahjuningrum, Ardiyansyah Syahrom

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

This study employs a computational approach to analyse the impact of morphological changes on the structural properties of biodegradable porous Mg subjected to a dynamic immersion test for its application as a bone scaffold. Porous Mg was immersed in a dynamic immersion test for 24, 48, and 72 h. Twelve specimens were prepared and scanned using micro-CT and then reconstructed into a 3D model for finite element analysis. The structural properties from the numerical simulation were then compared to the experimental values. Correlations between morphological parameters, structural properties, and fracture type were then made. The relative losses were observed to be in agreement with relative mass loss done experimentally. The degradation rates determined using exact (degraded) surface area at particular immersion times were on average 20% higher than the degradation rates obtained using original surface area. The dynamic degradation has significantly impacted the morphological changes of porous Mg in volume fraction, surface area, and trabecular separation, which in turn affects its structural properties and increases the immersion time.

Original languageEnglish
Pages (from-to)797-811
Number of pages15
JournalBiomechanics and Modeling in Mechanobiology
Volume18
Issue number3
DOIs
Publication statusPublished - 15 Jun 2019

Keywords

  • Dynamic degradation
  • Dynamic immersion test
  • Finite element analyses
  • Morphological parameters
  • Porous magnesium

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