TY - JOUR
T1 - Impacts of dynamic degradation on the morphological and mechanical characterisation of porous magnesium scaffold
AU - Md Saad, Amir Putra
AU - Prakoso, Akbar Teguh
AU - Sulong, M. A.
AU - Basri, Hasan
AU - Wahjuningrum, Dian Agustin
AU - Syahrom, Ardiyansyah
N1 - Funding Information:
Acknowledgements This project was sponsored by Universiti Teknologi Malaysia (UTM) via the Potential Academic Staff (PAS) Grant scheme (Q.J130000.2724.03K09). The authors would like to thank the Research Management Centre, Universiti Teknologi Malaysia (UTM), for managing the project. Several authors of this present study are financially supported by the HIR-MOHE research grant initiative.
Publisher Copyright:
© 2019, Springer-Verlag GmbH Germany, part of Springer Nature.
PY - 2019/6/15
Y1 - 2019/6/15
N2 - This study employs a computational approach to analyse the impact of morphological changes on the structural properties of biodegradable porous Mg subjected to a dynamic immersion test for its application as a bone scaffold. Porous Mg was immersed in a dynamic immersion test for 24, 48, and 72 h. Twelve specimens were prepared and scanned using micro-CT and then reconstructed into a 3D model for finite element analysis. The structural properties from the numerical simulation were then compared to the experimental values. Correlations between morphological parameters, structural properties, and fracture type were then made. The relative losses were observed to be in agreement with relative mass loss done experimentally. The degradation rates determined using exact (degraded) surface area at particular immersion times were on average 20% higher than the degradation rates obtained using original surface area. The dynamic degradation has significantly impacted the morphological changes of porous Mg in volume fraction, surface area, and trabecular separation, which in turn affects its structural properties and increases the immersion time.
AB - This study employs a computational approach to analyse the impact of morphological changes on the structural properties of biodegradable porous Mg subjected to a dynamic immersion test for its application as a bone scaffold. Porous Mg was immersed in a dynamic immersion test for 24, 48, and 72 h. Twelve specimens were prepared and scanned using micro-CT and then reconstructed into a 3D model for finite element analysis. The structural properties from the numerical simulation were then compared to the experimental values. Correlations between morphological parameters, structural properties, and fracture type were then made. The relative losses were observed to be in agreement with relative mass loss done experimentally. The degradation rates determined using exact (degraded) surface area at particular immersion times were on average 20% higher than the degradation rates obtained using original surface area. The dynamic degradation has significantly impacted the morphological changes of porous Mg in volume fraction, surface area, and trabecular separation, which in turn affects its structural properties and increases the immersion time.
KW - Dynamic degradation
KW - Dynamic immersion test
KW - Finite element analyses
KW - Morphological parameters
KW - Porous magnesium
UR - http://www.scopus.com/inward/record.url?scp=85059524226&partnerID=8YFLogxK
U2 - 10.1007/s10237-018-01115-z
DO - 10.1007/s10237-018-01115-z
M3 - Article
C2 - 30607641
AN - SCOPUS:85059524226
SN - 1617-7959
VL - 18
SP - 797
EP - 811
JO - Biomechanics and Modeling in Mechanobiology
JF - Biomechanics and Modeling in Mechanobiology
IS - 3
ER -