Immunoglobulin subclass in experimental murine Toxocara cati infection

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2 Citations (Scopus)


Aim: The aim of this study was to detect specific immunoglobulin (Ig) that could be used to determine monoclonal antibody in conjugate-making an effort for the indirect enzyme-linked immunosorbent assay (ELISA) diagnostic kit of toxocariasis in human. Materials and Methods: The study was conducted to assess the Ig profile, based on ELISA-isotyping, in mice infected with second stage larvae eggs of Toxocara cati. The optical density values of anti-T. cati mice serum IgG subclasses were analyzed by applying ANOVA factorial. Results: The specific IgG subclass in mice infected with T. cati mice was found to be IgG2β. Conclusion: Subclass of IgG, especially IgG2β, can provide leads about the use of the monoclonal antibody in conjugate making an effort for the indirect ELISA diagnostic kit.

Original languageEnglish
Pages (from-to)1333-1336
Number of pages4
JournalVeterinary World
Issue number11
Publication statusPublished - 13 Nov 2017


  • Diagnostic kit
  • Enzyme-linked immunosorbent assay
  • Human
  • Immunoglobulin G subclass
  • Monoclonal antibody
  • Toxocara cati
  • Toxocariasis


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