TY - JOUR
T1 - Immunobioinformatics of rabies virus in various countries of asia
T2 - Glycoprotein gene
AU - Fadholly, Amaq
AU - Ansori, Arif N.M.
AU - Kharisma, Viol D.
AU - Rahmahani, Jola
AU - Tacharina, Martia R.
N1 - Publisher Copyright:
© RJPT All right reserved.
PY - 2021/2
Y1 - 2021/2
N2 - The purpose of this study was to analyze the genomic information of the glycoprotein gene of rabies virus (RABV) in several countries of Asia. The genomics information of vaccine virus strain and some local isolates were retrieved from GeneBank® (National Center for Biotechnology Information, USA). Ten genomics informations are consist of ERA vaccine virus, two viruses from Indonesia, a virus from Myanmar, India, Nepal, South Korea, Japan, Sri Lanka, and Iran. This bioinformatics process the ten genomics data in order to find pattern in 1,575 bp of glycoprotein gene of RABV. In conclusion, this study have revealed the data of homology, B-cell epitope prediction, genetic distance, and molecular phylogenic analysis of RABV in various countries of Asia. We indicated that the glycoprotein, the immunogenic surface protein of RABV, has important part for vaccine design.
AB - The purpose of this study was to analyze the genomic information of the glycoprotein gene of rabies virus (RABV) in several countries of Asia. The genomics information of vaccine virus strain and some local isolates were retrieved from GeneBank® (National Center for Biotechnology Information, USA). Ten genomics informations are consist of ERA vaccine virus, two viruses from Indonesia, a virus from Myanmar, India, Nepal, South Korea, Japan, Sri Lanka, and Iran. This bioinformatics process the ten genomics data in order to find pattern in 1,575 bp of glycoprotein gene of RABV. In conclusion, this study have revealed the data of homology, B-cell epitope prediction, genetic distance, and molecular phylogenic analysis of RABV in various countries of Asia. We indicated that the glycoprotein, the immunogenic surface protein of RABV, has important part for vaccine design.
KW - Bioinformatics
KW - Glycoprotein
KW - Lyssavirus
KW - Rabies
KW - Vaccine
UR - http://www.scopus.com/inward/record.url?scp=85117872280&partnerID=8YFLogxK
U2 - 10.5958/0974-360X.2021.00157.8
DO - 10.5958/0974-360X.2021.00157.8
M3 - Article
AN - SCOPUS:85117872280
SN - 0974-3618
VL - 14
SP - 883
EP - 886
JO - Research Journal of Pharmacy and Technology
JF - Research Journal of Pharmacy and Technology
IS - 2
ER -