How prevalant are Plasmodium ovale and P. malariae in East Asia?

F. Kawamoto, Hiko Kawamoto, Qing Liu, Marcelo U. Ferreira, Indah S. Tantular

Research output: Contribution to journalShort surveypeer-review

59 Citations (Scopus)


Plasmodium ovale and Plasmodium malariae, two of the four human malaria parasites, are usually found at very low prevalence in East Asia, even in areas with intense malaria transmission. In this article, Fumihiko Kawamoto, Qing Liu, Marcelo Ferreira and Indah Tantular review data obtained in recent field surveys, using alternative diagnostic methods such as acridine orange staining and PCR-based methods, to evaluate the prevalence of these two malaria species in East Asia. They argue that these species might be much more prevalent in East Asia than reported previously. In addition, they discuss the implications of sequence variations found in the small subunit ribosomal RNA genes of the two species targeted by diagnostic PCR and compare morphological criteria for speciation of malaria parasites stained with Giemsa and acridine orange.

Original languageEnglish
Pages (from-to)422-426
Number of pages5
JournalParasitology Today
Issue number10
Publication statusPublished - 1 Oct 1999


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