TY - JOUR
T1 - How prevalant are Plasmodium ovale and P. malariae in East Asia?
AU - Kawamoto, F.
AU - Kawamoto, Hiko
AU - Liu, Qing
AU - Ferreira, Marcelo U.
AU - Tantular, Indah S.
N1 - Funding Information:
We thank Sue Fleck and Yoichi Yamagata for critical reading of the manuscript, and also the many collaborators and Health Ministries in East Asia. This study was supported by the Toyota Foundation (96B3-011); Grant-in-Aid for International Scientific Research: Field Survey (07041159, 09041179), Grant-in-Aid for Priority Areas (08281207, 09270210, 10166209), Grant-in-Aid for Scientific Research (A, 09309010) from the Japanese Ministry of Education, Science, Culture, and Sports, Japan; and partly by a grant for International Medical Cooperation from the Japanese Ministry of Health and Welfare. The Indonesian survey was supported by the large-scale cooperative program (No. 2) from the Japanese Society for Promotion of Science (JSPS).
PY - 1999/10/1
Y1 - 1999/10/1
N2 - Plasmodium ovale and Plasmodium malariae, two of the four human malaria parasites, are usually found at very low prevalence in East Asia, even in areas with intense malaria transmission. In this article, Fumihiko Kawamoto, Qing Liu, Marcelo Ferreira and Indah Tantular review data obtained in recent field surveys, using alternative diagnostic methods such as acridine orange staining and PCR-based methods, to evaluate the prevalence of these two malaria species in East Asia. They argue that these species might be much more prevalent in East Asia than reported previously. In addition, they discuss the implications of sequence variations found in the small subunit ribosomal RNA genes of the two species targeted by diagnostic PCR and compare morphological criteria for speciation of malaria parasites stained with Giemsa and acridine orange.
AB - Plasmodium ovale and Plasmodium malariae, two of the four human malaria parasites, are usually found at very low prevalence in East Asia, even in areas with intense malaria transmission. In this article, Fumihiko Kawamoto, Qing Liu, Marcelo Ferreira and Indah Tantular review data obtained in recent field surveys, using alternative diagnostic methods such as acridine orange staining and PCR-based methods, to evaluate the prevalence of these two malaria species in East Asia. They argue that these species might be much more prevalent in East Asia than reported previously. In addition, they discuss the implications of sequence variations found in the small subunit ribosomal RNA genes of the two species targeted by diagnostic PCR and compare morphological criteria for speciation of malaria parasites stained with Giemsa and acridine orange.
UR - http://www.scopus.com/inward/record.url?scp=0033211486&partnerID=8YFLogxK
U2 - 10.1016/S0169-4758(99)01511-2
DO - 10.1016/S0169-4758(99)01511-2
M3 - Short survey
C2 - 10481157
AN - SCOPUS:0033211486
SN - 0169-4758
VL - 15
SP - 422
EP - 426
JO - Parasitology Today
JF - Parasitology Today
IS - 10
ER -