@inbook{f7c0518a712d4576a5f2e3e4e057e65d,
title = "Histomorphometric Analysis of Anti-Aging Properties on Rat Skin",
abstract = "We present a histomorphometric analysis to enable quantitative measurement of anti-aging activity of topical substances in rat skin. In this method, the measured parameters were closely related to changes that occur on the skin caused by exposure to UV light. We used this protocol to determine the anti-aging activities of an ethanolic extract of Curcuma heyneana rhizome and retinoic acid by a measurement of the changes in epidermal thickness, the number of sunburned cells, the number of fibroblasts, and the space between collagen fibers.",
keywords = "Anti-aging assay, Curcuma heyneana rhizome, Histomorphometric analysis, Skin, UV rays",
author = "Idha Kusumawati and Kurniawan, {Kresma Oky} and Subhan Rullyansyah and Hestianah, {Eka Pramyrtha}",
note = "Publisher Copyright: {\textcopyright} 2020, Springer Science+Business Media, LLC, part of Springer Nature.",
year = "2020",
doi = "10.1007/978-1-0716-0471-7_22",
language = "English",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "313--321",
booktitle = "Methods in Molecular Biology",
}