Herpes zoster in COVID-19 patient: A coexistence or coincidence?

Afif Nurul Hidayati, Indah Purnamasari, Felix Hartanto, Tessa Thendria, Soraya Isfandiary Iskandar, Dewi Nurasrifah, Yuri Widia, Medhi Denisa Alinda

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Varicella-Zoster Virus (VZV) reactivation has been identified during the acute or subacute stages of COVID-19 infection. This phenomenon may be attributed to immune changes in COVID-19 patients, such as dysregulation and fatigue of the cellular immunity. We report a case of COVID-19 patient with herpes zoster (HZ). A 26-year-old woman was consulted for painful red patches and blisters on her right cheek. She has previously been diagnosed with and treated for COVID-19 and mild pneumonia 10 days prior. A herpetiform distribution of vesicles was observed spreading according to the branch of the trigeminal nerve innervation. The findings led to a clinical diagnosis of HZ. We recommended the standard acyclovir regimen in addition to the oseltamivir prescribed by the pulmonologist. The symptoms were completely resolved after seven days of acyclovir treatment, with no further complications. This was to our knowledge, the first case of HZ in COVID-19 reported in our country.

Original languageEnglish
Pages (from-to)182-184
Number of pages3
JournalMalaysian Journal of Medicine and Health Sciences
Publication statusPublished - Jun 2021


  • COVID-19
  • Herpes zoster
  • Immune response


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