TY - JOUR
T1 - Henoch-Schönlein Purpura (Childhood Immunoglobulin A Vasculitis) Caused by Dental Infection in One of Fraternal Twins
T2 - A Case Report
AU - Nelwan, Sindy Cornelia
AU - Puteri, Mega Moeharyono
AU - Tedjosasongko, Udijanto
AU - Saskianti, Tania
AU - Dharmawan, Devi
N1 - Publisher Copyright:
© 2022 University of the Philippines Manila. All rights reserved.
PY - 2022
Y1 - 2022
N2 - Henoch-Schönlein purpura (HSP) is the most common form of vasculitis in children that is clinically characterized by the classic triad of palpable purpura, joint symptoms, and abdominal pain. A 6-year-old girl, one of fraternal twins, was admitted to the Pediatric Department, Universitas Airlangga with fever, rashes on legs and arms and intermittent mild abdominal pain. She had multiple purpuric rashes on her extremities, abdomen and buttocks. Laboratory investigation revealed immunoglobulin A level of 289.6 mg/dL. The patient was diagnosed as HSP vasculitis according to EULAR criteria and treated with intravenous methylprednisolone. She was discharged after three days with normal physical examination and laboratory findings. Intraoral examination showed dental infection in the upper tooth region. The paediatrician suspected a correlation between HSP and her dental infection. The dental infection and genetic susceptibility may be the stimulant factors for the autoimmune reactions that caused HSP vasculitis. Hence, it might be useful to investigate the presence of dental infection in the etiology of HSP cases.
AB - Henoch-Schönlein purpura (HSP) is the most common form of vasculitis in children that is clinically characterized by the classic triad of palpable purpura, joint symptoms, and abdominal pain. A 6-year-old girl, one of fraternal twins, was admitted to the Pediatric Department, Universitas Airlangga with fever, rashes on legs and arms and intermittent mild abdominal pain. She had multiple purpuric rashes on her extremities, abdomen and buttocks. Laboratory investigation revealed immunoglobulin A level of 289.6 mg/dL. The patient was diagnosed as HSP vasculitis according to EULAR criteria and treated with intravenous methylprednisolone. She was discharged after three days with normal physical examination and laboratory findings. Intraoral examination showed dental infection in the upper tooth region. The paediatrician suspected a correlation between HSP and her dental infection. The dental infection and genetic susceptibility may be the stimulant factors for the autoimmune reactions that caused HSP vasculitis. Hence, it might be useful to investigate the presence of dental infection in the etiology of HSP cases.
KW - Henoch-Schönlein purpura
KW - dental infection
KW - fraternal twins
UR - http://www.scopus.com/inward/record.url?scp=85142107527&partnerID=8YFLogxK
U2 - 10.47895/amp.v56i17.2185
DO - 10.47895/amp.v56i17.2185
M3 - Article
AN - SCOPUS:85142107527
SN - 0001-6071
VL - 56
SP - 77
EP - 81
JO - Acta Medica Philippina
JF - Acta Medica Philippina
IS - 17
ER -