Global Prevalence and Potential Influencing Factors of COVID-19 Vaccination Hesitancy: A Meta-Analysis

Jonny Karunia Fajar; Malik Sallam; Gatot Soegiarto; Yani Jane Sugiri; Muhammad Anshory; Laksmi Wulandari; Stephanie Astrid Puspitasari Kosasih; Muhammad Ilmawan; Kusnaeni Kusnaeni; Muhammad Fikri; Frilianty Putri; Baitul Hamdi; Izza Dinalhaque Pranatasari; Lily Aina; Lailatul Maghfiroh; Fernanda Septi Ikhriandanti; Wa Ode Endiaverni; Krisna Wahyu Nugraha; Ory Wiranudirja; Sally Edinov; Ujang Hamdani; Lathifatul Rosyidah; Hanny Lubaba; Rinto Ariwibowo; Riska Andistyani; Ria Fitriani; Miftahul Hasanah; Fardha Ad Durrun Nafis; Fredo Tamara; Fitri Olga Latamu; Hendrix Indra Kusuma; Ali A. Rabaan; Saad Alhumaid; Abbas Al Mutair; Mohammed Garout; Muhammad A. Halwani; Mubarak Alfaresi; Reyouf Al Azmi; Nada A. Alasiri; Abeer N. Alshukairi; Kuldeep Dhama; Harapan Harapan

doi:10.3390/vaccines10081356

Global Prevalence and Potential Influencing Factors of COVID-19 Vaccination Hesitancy: A Meta-Analysis

Jonny Karunia Fajar, Malik Sallam, Gatot Soegiarto, Yani Jane Sugiri, Muhammad Anshory, Laksmi Wulandari, Stephanie Astrid Puspitasari Kosasih, Muhammad Ilmawan, Kusnaeni Kusnaeni, Muhammad Fikri, Frilianty Putri, Baitul Hamdi, Izza Dinalhaque Pranatasari, Lily Aina, Lailatul Maghfiroh, Fernanda Septi Ikhriandanti, Wa Ode Endiaverni, Krisna Wahyu Nugraha, Ory Wiranudirja, Sally EdinovUjang Hamdani, Lathifatul Rosyidah, Hanny Lubaba, Rinto Ariwibowo, Riska Andistyani, Ria Fitriani, Miftahul Hasanah, Fardha Ad Durrun Nafis, Fredo Tamara, Fitri Olga Latamu, Hendrix Indra Kusuma, Ali A. Rabaan, Saad Alhumaid, Abbas Al Mutair, Mohammed Garout, Muhammad A. Halwani, Mubarak Alfaresi, Reyouf Al Azmi, Nada A. Alasiri, Abeer N. Alshukairi, Kuldeep Dhama, Harapan Harapan

Research output: Contribution to journal › Review article › peer-review

80 Citations (Scopus)

Abstract

Countries worldwide have deployed mass COVID-19 vaccination drives, but there are people who are hesitant to receive the vaccine. Studies assessing the factors associated with COVID-19 vaccination hesitancy are inconclusive. This study aimed to assess the global prevalence of COVID-19 vaccination hesitancy and determine the potential factors associated with such hesitancy. We performed an organized search for relevant articles in PubMed, Scopus, and Web of Science. Extraction of the required information was performed for each study. A single-arm meta-analysis was performed to determine the global prevalence of COVID-19 vaccination hesitancy; the potential factors related to vaccine hesitancy were analyzed using a Z-test. A total of 56 articles were included in our analysis. We found that the global prevalence of COVID-19 vaccination hesitancy was 25%. Being a woman, being a 50-year-old or younger, being single, being unemployed, living in a household with five or more individuals, having an educational attainment lower than an undergraduate degree, having a non-healthcare-related job and considering COVID-19 vaccines to be unsafe were associated with a higher risk of vaccination hesitancy. In contrast, living with children at home, maintaining physical distancing norms, having ever tested for COVID-19, and having a history of influenza vaccination in the past few years were associated with a lower risk of hesitancy to COVID-19 vaccination. Our study provides valuable information on COVID-19 vaccination hesitancy, and we recommend special interventions in the sub-populations with increased risk to reduce COVID-19 vaccine hesitancy.

Original language	English
Article number	1356
Journal	Vaccines
Volume	10
Issue number	8
DOIs	https://doi.org/10.3390/vaccines10081356
Publication status	Published - Aug 2022

Keywords

COVID-19
acceptance
hesitancy
prevalence
vaccination

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.3390/vaccines10081356

Cite this

Fajar, J. K., Sallam, M., Soegiarto, G., Sugiri, Y. J., Anshory, M., Wulandari, L., Kosasih, S. A. P., Ilmawan, M., Kusnaeni, K., Fikri, M., Putri, F., Hamdi, B., Pranatasari, I. D., Aina, L., Maghfiroh, L., Ikhriandanti, F. S., Endiaverni, W. O., Nugraha, K. W., Wiranudirja, O., ... Harapan, H. (2022). Global Prevalence and Potential Influencing Factors of COVID-19 Vaccination Hesitancy: A Meta-Analysis. Vaccines, 10(8), Article 1356. https://doi.org/10.3390/vaccines10081356

@article{03df9fab85b845c7a4126c31062ea7db,

title = "Global Prevalence and Potential Influencing Factors of COVID-19 Vaccination Hesitancy: A Meta-Analysis",

abstract = "Countries worldwide have deployed mass COVID-19 vaccination drives, but there are people who are hesitant to receive the vaccine. Studies assessing the factors associated with COVID-19 vaccination hesitancy are inconclusive. This study aimed to assess the global prevalence of COVID-19 vaccination hesitancy and determine the potential factors associated with such hesitancy. We performed an organized search for relevant articles in PubMed, Scopus, and Web of Science. Extraction of the required information was performed for each study. A single-arm meta-analysis was performed to determine the global prevalence of COVID-19 vaccination hesitancy; the potential factors related to vaccine hesitancy were analyzed using a Z-test. A total of 56 articles were included in our analysis. We found that the global prevalence of COVID-19 vaccination hesitancy was 25%. Being a woman, being a 50-year-old or younger, being single, being unemployed, living in a household with five or more individuals, having an educational attainment lower than an undergraduate degree, having a non-healthcare-related job and considering COVID-19 vaccines to be unsafe were associated with a higher risk of vaccination hesitancy. In contrast, living with children at home, maintaining physical distancing norms, having ever tested for COVID-19, and having a history of influenza vaccination in the past few years were associated with a lower risk of hesitancy to COVID-19 vaccination. Our study provides valuable information on COVID-19 vaccination hesitancy, and we recommend special interventions in the sub-populations with increased risk to reduce COVID-19 vaccine hesitancy.",

keywords = "COVID-19, acceptance, hesitancy, prevalence, vaccination",

author = "Fajar, {Jonny Karunia} and Malik Sallam and Gatot Soegiarto and Sugiri, {Yani Jane} and Muhammad Anshory and Laksmi Wulandari and Kosasih, {Stephanie Astrid Puspitasari} and Muhammad Ilmawan and Kusnaeni Kusnaeni and Muhammad Fikri and Frilianty Putri and Baitul Hamdi and Pranatasari, {Izza Dinalhaque} and Lily Aina and Lailatul Maghfiroh and Ikhriandanti, {Fernanda Septi} and Endiaverni, {Wa Ode} and Nugraha, {Krisna Wahyu} and Ory Wiranudirja and Sally Edinov and Ujang Hamdani and Lathifatul Rosyidah and Hanny Lubaba and Rinto Ariwibowo and Riska Andistyani and Ria Fitriani and Miftahul Hasanah and Nafis, {Fardha Ad Durrun} and Fredo Tamara and Latamu, {Fitri Olga} and Kusuma, {Hendrix Indra} and Rabaan, {Ali A.} and Saad Alhumaid and Mutair, {Abbas Al} and Mohammed Garout and Halwani, {Muhammad A.} and Mubarak Alfaresi and {Al Azmi}, Reyouf and Alasiri, {Nada A.} and Alshukairi, {Abeer N.} and Kuldeep Dhama and Harapan Harapan",

note = "Publisher Copyright: {\textcopyright} 2022 by the authors.",

year = "2022",

month = aug,

doi = "10.3390/vaccines10081356",

language = "English",

volume = "10",

journal = "Vaccines",

issn = "2076-393X",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "8",

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Fajar, JK, Sallam, M, Soegiarto, G, Sugiri, YJ, Anshory, M, Wulandari, L, Kosasih, SAP, Ilmawan, M, Kusnaeni, K, Fikri, M, Putri, F, Hamdi, B, Pranatasari, ID, Aina, L, Maghfiroh, L, Ikhriandanti, FS, Endiaverni, WO, Nugraha, KW, Wiranudirja, O, Edinov, S, Hamdani, U, Rosyidah, L, Lubaba, H, Ariwibowo, R, Andistyani, R, Fitriani, R, Hasanah, M, Nafis, FAD, Tamara, F, Latamu, FO, Kusuma, HI, Rabaan, AA, Alhumaid, S, Mutair, AA, Garout, M, Halwani, MA, Alfaresi, M, Al Azmi, R, Alasiri, NA, Alshukairi, AN, Dhama, K & Harapan, H 2022, 'Global Prevalence and Potential Influencing Factors of COVID-19 Vaccination Hesitancy: A Meta-Analysis', Vaccines, vol. 10, no. 8, 1356. https://doi.org/10.3390/vaccines10081356

TY - JOUR

T1 - Global Prevalence and Potential Influencing Factors of COVID-19 Vaccination Hesitancy

T2 - A Meta-Analysis

AU - Fajar, Jonny Karunia

AU - Sallam, Malik

AU - Soegiarto, Gatot

AU - Sugiri, Yani Jane

AU - Anshory, Muhammad

AU - Wulandari, Laksmi

AU - Kosasih, Stephanie Astrid Puspitasari

AU - Ilmawan, Muhammad

AU - Kusnaeni, Kusnaeni

AU - Fikri, Muhammad

AU - Putri, Frilianty

AU - Hamdi, Baitul

AU - Pranatasari, Izza Dinalhaque

AU - Aina, Lily

AU - Maghfiroh, Lailatul

AU - Ikhriandanti, Fernanda Septi

AU - Endiaverni, Wa Ode

AU - Nugraha, Krisna Wahyu

AU - Wiranudirja, Ory

AU - Edinov, Sally

AU - Hamdani, Ujang

AU - Rosyidah, Lathifatul

AU - Lubaba, Hanny

AU - Ariwibowo, Rinto

AU - Andistyani, Riska

AU - Fitriani, Ria

AU - Hasanah, Miftahul

AU - Nafis, Fardha Ad Durrun

AU - Tamara, Fredo

AU - Latamu, Fitri Olga

AU - Kusuma, Hendrix Indra

AU - Rabaan, Ali A.

AU - Alhumaid, Saad

AU - Mutair, Abbas Al

AU - Garout, Mohammed

AU - Halwani, Muhammad A.

AU - Alfaresi, Mubarak

AU - Al Azmi, Reyouf

AU - Alasiri, Nada A.

AU - Alshukairi, Abeer N.

AU - Dhama, Kuldeep

AU - Harapan, Harapan

PY - 2022/8

Y1 - 2022/8

N2 - Countries worldwide have deployed mass COVID-19 vaccination drives, but there are people who are hesitant to receive the vaccine. Studies assessing the factors associated with COVID-19 vaccination hesitancy are inconclusive. This study aimed to assess the global prevalence of COVID-19 vaccination hesitancy and determine the potential factors associated with such hesitancy. We performed an organized search for relevant articles in PubMed, Scopus, and Web of Science. Extraction of the required information was performed for each study. A single-arm meta-analysis was performed to determine the global prevalence of COVID-19 vaccination hesitancy; the potential factors related to vaccine hesitancy were analyzed using a Z-test. A total of 56 articles were included in our analysis. We found that the global prevalence of COVID-19 vaccination hesitancy was 25%. Being a woman, being a 50-year-old or younger, being single, being unemployed, living in a household with five or more individuals, having an educational attainment lower than an undergraduate degree, having a non-healthcare-related job and considering COVID-19 vaccines to be unsafe were associated with a higher risk of vaccination hesitancy. In contrast, living with children at home, maintaining physical distancing norms, having ever tested for COVID-19, and having a history of influenza vaccination in the past few years were associated with a lower risk of hesitancy to COVID-19 vaccination. Our study provides valuable information on COVID-19 vaccination hesitancy, and we recommend special interventions in the sub-populations with increased risk to reduce COVID-19 vaccine hesitancy.

AB - Countries worldwide have deployed mass COVID-19 vaccination drives, but there are people who are hesitant to receive the vaccine. Studies assessing the factors associated with COVID-19 vaccination hesitancy are inconclusive. This study aimed to assess the global prevalence of COVID-19 vaccination hesitancy and determine the potential factors associated with such hesitancy. We performed an organized search for relevant articles in PubMed, Scopus, and Web of Science. Extraction of the required information was performed for each study. A single-arm meta-analysis was performed to determine the global prevalence of COVID-19 vaccination hesitancy; the potential factors related to vaccine hesitancy were analyzed using a Z-test. A total of 56 articles were included in our analysis. We found that the global prevalence of COVID-19 vaccination hesitancy was 25%. Being a woman, being a 50-year-old or younger, being single, being unemployed, living in a household with five or more individuals, having an educational attainment lower than an undergraduate degree, having a non-healthcare-related job and considering COVID-19 vaccines to be unsafe were associated with a higher risk of vaccination hesitancy. In contrast, living with children at home, maintaining physical distancing norms, having ever tested for COVID-19, and having a history of influenza vaccination in the past few years were associated with a lower risk of hesitancy to COVID-19 vaccination. Our study provides valuable information on COVID-19 vaccination hesitancy, and we recommend special interventions in the sub-populations with increased risk to reduce COVID-19 vaccine hesitancy.

KW - COVID-19

KW - acceptance

KW - hesitancy

KW - prevalence

KW - vaccination

UR - http://www.scopus.com/inward/record.url?scp=85138081515&partnerID=8YFLogxK

U2 - 10.3390/vaccines10081356

DO - 10.3390/vaccines10081356

M3 - Review article

AN - SCOPUS:85138081515

SN - 2076-393X

VL - 10

JO - Vaccines

JF - Vaccines

IS - 8

M1 - 1356

ER -

Global Prevalence and Potential Influencing Factors of COVID-19 Vaccination Hesitancy: A Meta-Analysis

Abstract

Keywords

UN SDGs

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