Gambaran Nekrosis Hepar Mencit yang Diinduksi Monosodium Glutamat dan Ekstrak Methanol Biji Kopi Robusta (Coffea Canephora)

Translated title of the contribution: Necrosis description of mice liver induced with monosodium glutamate and methanol robusta coffee bean extract (Coffea canephora)

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3 Citations (Scopus)

Abstract

This study aimed to analyze the effect of methanol robusta coffee bean extract (Coffea canephora) on liver histopathological description in mice induced with monosodium glutamate (MSG). This study was used 20 male mice for 5 treatment groups: K + (MSG 0.12 mg and Vitamin C 6 mg), K- (MSG 0.12 mg and CMC Na 0.1 ml), P1 (MSG 0.12 mg andRCE 0.1 mg), P2 (MSG 0.12 mg andRCE 0.2 mg), andP3 (MSG 0.12 mg andRCE 0.4 mg) per orally for 42 days. Liver histological scores were analyzed using Kruskal Wallis test. The results of Kruskal Wallis test scoredp=0,391 which indicates that the data is not significant (p>0.05). In the control and treatment groups there were no significant. In conclusion, the giving methanol robusta coffee bean extract did not show a decrease in hepatosite damage that was different from the negative control treatment group.

Translated title of the contributionNecrosis description of mice liver induced with monosodium glutamate and methanol robusta coffee bean extract (Coffea canephora)
Original languageIndonesian
Pages (from-to)213-220
Number of pages8
JournalJurnal Medik Veteriner
Volume4
Issue number2
DOIs
Publication statusPublished - Oct 2021

Keywords

  • Coffea canephora
  • Liver
  • Monosodium glutamate
  • Mus musculus

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