FUCOIDAN FROM Sargassum plagiophyllum BY MICROWAVE ASSISTED EXTRACTION IN COMPARISON WITH CONVENTIONAL METHODS

Sargassum is a brown seaweed rich in fucoidan which is a sulfated polysaccharide. This study aims to examine the conventional and microwave-assisted extraction (MAE) methods to optimize fucoidan extraction from Sargassum plagiophyllum with 0.1 M HCl and water solvents. The extraction of fucoidan was conducted in two different methods, conventional (C) and MAE (M) methods. Microwave-assisted extraction was performed at 450, 600, and 700 W microwave power for five minutes, then the extracted fucoidan was determined for its sulfate and fucose contents, as well as antioxidant activities. In both the conventional (CAwe) and MAE methods (MAfa7), the maximum yields of fucoidan crude extract produced in 0.1 M HCl solvent were 19.10 and 19.20%, respectively. The highest sulfate (MAfa7; 6.14%), and fucose content (MAaf7; 5.95 mg/100g) were found in the HCl solvent using the MAE method. Based on the results, the MAE approach with HCl solvent was a more efficient technology for extracting fucoidan from S. plagiophyllum than the conventional method.