First total synthesis of cassiarin A, a naturally occurring potent antiplasmodial alkaloid

Marcellino Rudyanto, Yuichiro Tomizawa, Hiroshi Morita, Toshio Honda

Research output: Contribution to journalArticlepeer-review

38 Citations (Scopus)

Abstract

The first total synthesis of cassiarin A, an antiplasmodial alkaloid isolated from Cassia siamea, was achieved via sequential alkynylation of arenes with Sonogashira coupling and 6-endo-dig-cyclization of phenolic oxygens to the resulting alkynes.

Original languageEnglish
Pages (from-to)1921-1922
Number of pages2
JournalOrganic Letters
Volume10
Issue number10
DOIs
Publication statusPublished - 15 May 2008

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