TY - JOUR
T1 - Firmosides A and B
T2 - two new sucrose ferulates from the aerial parts of Silene firma and evaluation of radical scavenging activities
AU - Uyen, Nguyen Hoang
AU - Widyowati, Retno
AU - Sulistyowaty, Melanny Ika
AU - Sugimoto, Sachiko
AU - Yamano, Yoshi
AU - Kawakami, Susumu
AU - Otsuka, Hideaki
AU - Matsunami, Katsuyoshi
N1 - Funding Information:
The authors are grateful for access to the superconducting NMR instrument (Bruker Avance 600, JEOL ECA600) and Thermo Fisher Scientific LTQ Orbitrap XL spectrometer at the Analysis Center of Life Science, Natural Science Center for Basic Research and Development, Hiroshima University. This work was supported by JSPS KAKENHI (18K06740, 17K15465, 17K08336), the Cosmetology Research Foundation, and the Japan Food Chemical Research Foundation.
Funding Information:
The authors are grateful for access to the superconducting NMR instrument (Bruker Avance 600, JEOL ECA600) and Thermo Fisher Scientific LTQ Orbitrap XL spectrometer at the Analysis Center of Life Science, Natural Science Center for Basic Research and Development, Hiroshima University. This work was supported by JSPS KAKENHI (18K06740, 17K15465, 17K08336), the Cosmetology Research Foundation, and the Japan Food Chemical Research Foundation.
Publisher Copyright:
© 2020, The Japanese Society of Pharmacognosy.
PY - 2020/9/1
Y1 - 2020/9/1
N2 - Abstract: Two new tri-ferulates of sucrose, firmosides A and B (1 and 2, respectively), together with 18 known compounds (3–20), were isolated from the aerial parts of Silene firma. The structures of the isolated compounds were elucidated by various spectroscopic methods, including 1D, 2D NMR, and high-resolution electro-spray ionization–mass spectrometry (HR-ESI–MS). All the isolated compounds were evaluated for their free radical scavenging activity using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical. As a result, two new compounds (1, 2) and 11 demonstrated significant radical scavenging activity, implying the usefulness as antioxidant agents. Graphic Abstract: [Figure not available: see fulltext.].
AB - Abstract: Two new tri-ferulates of sucrose, firmosides A and B (1 and 2, respectively), together with 18 known compounds (3–20), were isolated from the aerial parts of Silene firma. The structures of the isolated compounds were elucidated by various spectroscopic methods, including 1D, 2D NMR, and high-resolution electro-spray ionization–mass spectrometry (HR-ESI–MS). All the isolated compounds were evaluated for their free radical scavenging activity using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical. As a result, two new compounds (1, 2) and 11 demonstrated significant radical scavenging activity, implying the usefulness as antioxidant agents. Graphic Abstract: [Figure not available: see fulltext.].
KW - DPPH
KW - Ferulic acid
KW - Firmoside
KW - Radical scavenging activities
KW - Silene firma
KW - Sucrose
UR - http://www.scopus.com/inward/record.url?scp=85087558191&partnerID=8YFLogxK
U2 - 10.1007/s11418-020-01426-5
DO - 10.1007/s11418-020-01426-5
M3 - Article
C2 - 32632912
AN - SCOPUS:85087558191
SN - 1340-3443
VL - 74
SP - 796
EP - 803
JO - Journal of Natural Medicines
JF - Journal of Natural Medicines
IS - 4
ER -