Firmosides A and B: two new sucrose ferulates from the aerial parts of Silene firma and evaluation of radical scavenging activities

Nguyen Hoang Uyen; Retno Widyowati; Melanny Ika Sulistyowaty; Sachiko Sugimoto; Yoshi Yamano; Susumu Kawakami; Hideaki Otsuka; Katsuyoshi Matsunami

doi:10.1007/s11418-020-01426-5

Firmosides A and B: two new sucrose ferulates from the aerial parts of Silene firma and evaluation of radical scavenging activities

Nguyen Hoang Uyen, Retno Widyowati, Melanny Ika Sulistyowaty, Sachiko Sugimoto, Yoshi Yamano, Susumu Kawakami, Hideaki Otsuka, Katsuyoshi Matsunami

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Abstract: Two new tri-ferulates of sucrose, firmosides A and B (1 and 2, respectively), together with 18 known compounds (3–20), were isolated from the aerial parts of Silene firma. The structures of the isolated compounds were elucidated by various spectroscopic methods, including 1D, 2D NMR, and high-resolution electro-spray ionization–mass spectrometry (HR-ESI–MS). All the isolated compounds were evaluated for their free radical scavenging activity using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical. As a result, two new compounds (1, 2) and 11 demonstrated significant radical scavenging activity, implying the usefulness as antioxidant agents. Graphic Abstract: [Figure not available: see fulltext.].

Original language	English
Pages (from-to)	796-803
Number of pages	8
Journal	Journal of Natural Medicines
Volume	74
Issue number	4
DOIs	https://doi.org/10.1007/s11418-020-01426-5
Publication status	Published - 1 Sept 2020

Keywords

DPPH
Ferulic acid
Firmoside
Radical scavenging activities
Silene firma
Sucrose

Access to Document

10.1007/s11418-020-01426-5

Cite this

@article{05c63b0390914fb9a2e4e490df4348af,

title = "Firmosides A and B: two new sucrose ferulates from the aerial parts of Silene firma and evaluation of radical scavenging activities",

abstract = "Abstract: Two new tri-ferulates of sucrose, firmosides A and B (1 and 2, respectively), together with 18 known compounds (3–20), were isolated from the aerial parts of Silene firma. The structures of the isolated compounds were elucidated by various spectroscopic methods, including 1D, 2D NMR, and high-resolution electro-spray ionization–mass spectrometry (HR-ESI–MS). All the isolated compounds were evaluated for their free radical scavenging activity using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical. As a result, two new compounds (1, 2) and 11 demonstrated significant radical scavenging activity, implying the usefulness as antioxidant agents. Graphic Abstract: [Figure not available: see fulltext.].",

keywords = "DPPH, Ferulic acid, Firmoside, Radical scavenging activities, Silene firma, Sucrose",

author = "Uyen, {Nguyen Hoang} and Retno Widyowati and Sulistyowaty, {Melanny Ika} and Sachiko Sugimoto and Yoshi Yamano and Susumu Kawakami and Hideaki Otsuka and Katsuyoshi Matsunami",

note = "Publisher Copyright: {\textcopyright} 2020, The Japanese Society of Pharmacognosy.",

year = "2020",

month = sep,

day = "1",

doi = "10.1007/s11418-020-01426-5",

language = "English",

volume = "74",

pages = "796--803",

journal = "Journal of Natural Medicines",

issn = "1340-3443",

publisher = "Springer Japan",

number = "4",

}

TY - JOUR

T1 - Firmosides A and B

T2 - two new sucrose ferulates from the aerial parts of Silene firma and evaluation of radical scavenging activities

AU - Uyen, Nguyen Hoang

AU - Widyowati, Retno

AU - Sulistyowaty, Melanny Ika

AU - Sugimoto, Sachiko

AU - Yamano, Yoshi

AU - Kawakami, Susumu

AU - Otsuka, Hideaki

AU - Matsunami, Katsuyoshi

PY - 2020/9/1

Y1 - 2020/9/1

N2 - Abstract: Two new tri-ferulates of sucrose, firmosides A and B (1 and 2, respectively), together with 18 known compounds (3–20), were isolated from the aerial parts of Silene firma. The structures of the isolated compounds were elucidated by various spectroscopic methods, including 1D, 2D NMR, and high-resolution electro-spray ionization–mass spectrometry (HR-ESI–MS). All the isolated compounds were evaluated for their free radical scavenging activity using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical. As a result, two new compounds (1, 2) and 11 demonstrated significant radical scavenging activity, implying the usefulness as antioxidant agents. Graphic Abstract: [Figure not available: see fulltext.].

AB - Abstract: Two new tri-ferulates of sucrose, firmosides A and B (1 and 2, respectively), together with 18 known compounds (3–20), were isolated from the aerial parts of Silene firma. The structures of the isolated compounds were elucidated by various spectroscopic methods, including 1D, 2D NMR, and high-resolution electro-spray ionization–mass spectrometry (HR-ESI–MS). All the isolated compounds were evaluated for their free radical scavenging activity using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical. As a result, two new compounds (1, 2) and 11 demonstrated significant radical scavenging activity, implying the usefulness as antioxidant agents. Graphic Abstract: [Figure not available: see fulltext.].

KW - DPPH

KW - Ferulic acid

KW - Firmoside

KW - Radical scavenging activities

KW - Silene firma

KW - Sucrose

UR - http://www.scopus.com/inward/record.url?scp=85087558191&partnerID=8YFLogxK

U2 - 10.1007/s11418-020-01426-5

DO - 10.1007/s11418-020-01426-5

M3 - Article

C2 - 32632912

AN - SCOPUS:85087558191

SN - 1340-3443

VL - 74

SP - 796

EP - 803

JO - Journal of Natural Medicines

JF - Journal of Natural Medicines

IS - 4

ER -

Firmosides A and B: two new sucrose ferulates from the aerial parts of Silene firma and evaluation of radical scavenging activities

Abstract

Keywords

Access to Document

Fingerprint

Cite this