Firmosides A and B: two new sucrose ferulates from the aerial parts of Silene firma and evaluation of radical scavenging activities

Nguyen Hoang Uyen, Retno Widyowati, Melanny Ika Sulistyowaty, Sachiko Sugimoto, Yoshi Yamano, Susumu Kawakami, Hideaki Otsuka, Katsuyoshi Matsunami

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Abstract: Two new tri-ferulates of sucrose, firmosides A and B (1 and 2, respectively), together with 18 known compounds (3–20), were isolated from the aerial parts of Silene firma. The structures of the isolated compounds were elucidated by various spectroscopic methods, including 1D, 2D NMR, and high-resolution electro-spray ionization–mass spectrometry (HR-ESI–MS). All the isolated compounds were evaluated for their free radical scavenging activity using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical. As a result, two new compounds (1, 2) and 11 demonstrated significant radical scavenging activity, implying the usefulness as antioxidant agents. Graphic Abstract: [Figure not available: see fulltext.].

Original languageEnglish
Pages (from-to)796-803
Number of pages8
JournalJournal of Natural Medicines
Volume74
Issue number4
DOIs
Publication statusPublished - 1 Sept 2020

Keywords

  • DPPH
  • Ferulic acid
  • Firmoside
  • Radical scavenging activities
  • Silene firma
  • Sucrose

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