Background: Fecal calprotectin (FC) is one of fecal biomarkers that has validation to distinguish the organic and functional bowel disease but the relationship with disease activity in Spondyloarthritis (SpA) is still questionable. We determined the correlation of FC to the degree of disease activity on SpA. Material and Method: This cross sectional analytic study involved thirty-two subjects diagnosed with SpA. FC levels were analyzed using ELISA method. The Spondylartritis disease activities were assessed by ASDAS-CRP scores. Results: The median age was 52.5 (23.0-71.0) years with the average ASDAS-CRP score of 2.53 ± 0.61. The median level of FC increased by 58.15 (5.20-269.20) µg/g and was found to be positive (≥50 µg/g) in 56.3% subjects. FC levels was significantly correlated with the degree of SpA activity according to ASDAS-CRP scores (r = 0.563; P = 0.001) Conclusion: Fecal Calprotectin associated with the degree of activity in the SpA measured by ASDAS-CRP scores.

Original languageEnglish
Pages (from-to)1414-1419
Number of pages6
JournalInternational Journal of Pharmaceutical Research
Issue number3
Publication statusPublished - 1 Jul 2020


  • Disease activity
  • Fecal Calprotectin
  • Spondyloarthritis


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