TY - JOUR
T1 - Factors related to barriers and medication adherence in patients with type 2 diabetes mellitus
T2 - a cross-sectional study
AU - Zairina, Elida
AU - Nugraheni, Gesnita
AU - Sulistyarini, Arie
AU - Mufarrihah,
AU - Setiawan, Catur Dian
AU - Kripalani, Sunil
AU - Lestari, Safira Indah
N1 - Funding Information:
The authors would like to thank the Faculty of Pharmacy, Universitas Airlangga, and the Lembaga Penelitian dan Pengabdian Masyarakat (LPPM) Universitas Airlangga for the support and facilities provided during the study. We also thank the research assistants involved in this study: Ms. Yenni Desilia Indahsari, Ms. Edlia Fadilah and Ms. Yerlita El Girath.
Funding Information:
The authors disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by the Indonesian Ministry of Education and Culture [DRPM – PDUPT 2019-2021]. The funder had no role in the study design; in the collection, and analysis or interpretation of data; in the writing of the report; or in the decision to submit the article for publication.
Publisher Copyright:
© 2022, Springer Nature Switzerland AG.
PY - 2022/6
Y1 - 2022/6
N2 - Purpose: Evidence has shown that 50% of patients, including type 2 diabetes mellitus (DM), are non-adherent to the prescribed antidiabetic medication regimen. Some barriers lead to nonadherence in people with DM type 2. The study aimed to identify factors related to adherence in patient with DM and to assess the correlation between barriers to adherence type 2 DM patients. Methods: The cross-sectional study was conducted in 63 primary healthcare centers in Surabaya, Indonesia. Patients with DM type 2 were recruited between April and September 2019 using convenient sampling technique. Ethics approval was obtained (80/EA/KEPK/2019). Results: A total of 266 patients with type 2 DM participated in this study. Of the respondents, 201 (75.2%) were female. Unwanted drug effects, changes in medication regimens, and refilling the prescription when the drugs run out were most reported factors that affected adherence. Spearman correlations and linear regression tests were used to examine the relationship between barriers to medication adherence, and education with medication adherence. A significant difference was observed between the level of education and adherence (p = 0.031). The results showed an association between barriers to medication and adherence to medication (r = 0.304; p < 0.001) which was confirmed in regression analysis (R = 0.309, R square = 0.095, p <0.001). Conclusions: Barriers to adherence are common and affect adherence to therapy. It is essential to expand the roles of health care professionals in the community to include counseling, barrier-monitoring, education, and problem-solving to improve patient medication adherence.
AB - Purpose: Evidence has shown that 50% of patients, including type 2 diabetes mellitus (DM), are non-adherent to the prescribed antidiabetic medication regimen. Some barriers lead to nonadherence in people with DM type 2. The study aimed to identify factors related to adherence in patient with DM and to assess the correlation between barriers to adherence type 2 DM patients. Methods: The cross-sectional study was conducted in 63 primary healthcare centers in Surabaya, Indonesia. Patients with DM type 2 were recruited between April and September 2019 using convenient sampling technique. Ethics approval was obtained (80/EA/KEPK/2019). Results: A total of 266 patients with type 2 DM participated in this study. Of the respondents, 201 (75.2%) were female. Unwanted drug effects, changes in medication regimens, and refilling the prescription when the drugs run out were most reported factors that affected adherence. Spearman correlations and linear regression tests were used to examine the relationship between barriers to medication adherence, and education with medication adherence. A significant difference was observed between the level of education and adherence (p = 0.031). The results showed an association between barriers to medication and adherence to medication (r = 0.304; p < 0.001) which was confirmed in regression analysis (R = 0.309, R square = 0.095, p <0.001). Conclusions: Barriers to adherence are common and affect adherence to therapy. It is essential to expand the roles of health care professionals in the community to include counseling, barrier-monitoring, education, and problem-solving to improve patient medication adherence.
KW - Chronic illness
KW - Diabetes mellitus
KW - Drug adherence
KW - Patient compliance
KW - Primary care
UR - http://www.scopus.com/inward/record.url?scp=85123824589&partnerID=8YFLogxK
U2 - 10.1007/s40200-021-00961-6
DO - 10.1007/s40200-021-00961-6
M3 - Article
AN - SCOPUS:85123824589
SN - 2251-6581
VL - 21
SP - 219
EP - 228
JO - Journal of Diabetes and Metabolic Disorders
JF - Journal of Diabetes and Metabolic Disorders
IS - 1
ER -
