Ezetimibe

Maria L.A.D. Lestari, Febry Ardiana, Gunawan Indrayanto

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

21 Citations (Scopus)

Abstract

Ezetimibe is a drug substance which can be used for lowering low-density lipoprotein cholesterol. Its crystal form and polymorphism have been determined using X-ray diffraction and thermal methods. Quantitative and qualitative analysis of Ezetimibe as well as study of its impurities and degradations were summarized in this chapter.

Original languageEnglish
Title of host publicationProfiles of Drug Substances, Excipients and Related Methodology
PublisherAcademic Press Inc.
Pages103-149
Number of pages47
DOIs
Publication statusPublished - 2011

Publication series

NameProfiles of Drug Substances, Excipients and Related Methodology
Volume36
ISSN (Print)1871-5125

Keywords

  • Crystal form and polymorphism
  • Degradation of ezetimibe
  • Determination of ezetimibe in biological sample, X-ray diffraction, Thermogravimetric analysis, NMR.
  • Ezetimibe
  • Gas Chromatography
  • Impurities, UV spectrophotometry
  • Liquid Chromatography
  • Micellar Electrokinetic Capillary Chromatography
  • Thin Layer Chromatography

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