Expression of superoxide dismutase-2 (SOD2) and catalase (CAT) in the lens epithelial cells of mice: A comparative study of UV blocking protection by uv blocking glasses and UV blocking contact lenses

Cataract is a leading cause of global blindness, often associated with long-term sunlight exposure and UV-B radiation. This study investigates the protective effects of anti-UV-B glasses and contact lenses on the expression of superoxide dismutase-2 (SOD2) and catalase (CAT) in mice lens epithelial cells. UV-B exposure is known to induce oxidative stress and cataract formation by disrupting the balance of oxidant and antioxidant enzymes. Our study evaluates the role of SOD2 and CAT expression in response to UV blocking glasses and contact lenses. Results demonstrate a significant reduction in ROS generation and DNA damage in epithelial cells, suggesting the protective efficacy of these UV-blocking interventions.