In children younger than three years are considered as Severe Early Childhood Caries (S-ECC). This analytic observational study compared the level of CD8+ expression in saliva of children with S-ECC and free-caries children. Lymphocyte cells contained in saliva acquired by instructing the experimental subjects to gargle 10 ml of 1.5% NaCl solution. The expression of T lymphocyte (CD8+) was analyzed by means of flow cytometry. The expression of T lymphocyte (CD8+) in children with S-ECC (0.3400±0.14726) was higher than free-caries group (0.3250±0.11301) with P value of 0.655.

Original languageEnglish
Pages (from-to)227-231
Number of pages5
JournalAnnals of Biology
Issue number2
Publication statusPublished - Apr 2020


  • Adaptive immunity
  • S-ECC
  • T lymphocyte (CD8)


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