Evaluation of BSP and DMP1 in hydroxyapatite crab shells used for dental socket preservation

Michael Josef Kridanto Kamadjaja; Sherman Salim; Wiwik Herawati Waluyo; Tengku Natasha Eleena binti Tengku Ahmad Noor

doi:10.20473/J.DJMKG.V56.I2.P104-108

Evaluation of BSP and DMP1 in hydroxyapatite crab shells used for dental socket preservation

Michael Josef Kridanto Kamadjaja, Sherman Salim, Wiwik Herawati Waluyo, Tengku Natasha Eleena binti Tengku Ahmad Noor

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Background: Bone resorption due to tooth extraction leads to unpredictable bone volume for future prosthetics. Crab shells were promoted as a solution to prevent bone resorption, along with an effort to reduce biological waste. Purpose: This study aimed to analyze the expression of bone sialoprotein (BSP) and dentine matrix protein-1 (DMP1) in the wound healing process in tooth-extraction sockets after applying a crab shell-derived hydroxyapatite scaffold. Methods: The subjects (28 Cavia cobaya) were divided into control and treatment groups. The control group was left untreated, while the treatment group received a hydroxyapatite scaffold of Portunus pelagicus shell in the tooth socket. The expression of BSP and DMP1 was determined by immunohistochemical staining on days 7 and 14. One-way analysis of variance and Tukey’s honest significance difference test were used to find the groups with the most significant difference. Results: The highest mean expression of BSP and DMP1 was in the day 14 treatment group, while the lowest was in the day 7 control group. Conclusion: Administering hydroxyapatite scaffold derived from the Portunus pelagicus shell to the post-extraction sockets increased the expression of both BSP and DMP1.

Original language	English
Pages (from-to)	104-108
Number of pages	5
Journal	Dental Journal
Volume	56
Issue number	2
DOIs	https://doi.org/10.20473/J.DJMKG.V56.I2.P104-108
Publication status	Published - 2023

Keywords

BSP
DMP1
crab shell
hydroxyapatite
medicine

Access to Document

10.20473/J.DJMKG.V56.I2.P104-108

Cite this

@article{4012c25f7831437c93459289c802c928,

title = "Evaluation of BSP and DMP1 in hydroxyapatite crab shells used for dental socket preservation",

abstract = "Background: Bone resorption due to tooth extraction leads to unpredictable bone volume for future prosthetics. Crab shells were promoted as a solution to prevent bone resorption, along with an effort to reduce biological waste. Purpose: This study aimed to analyze the expression of bone sialoprotein (BSP) and dentine matrix protein-1 (DMP1) in the wound healing process in tooth-extraction sockets after applying a crab shell-derived hydroxyapatite scaffold. Methods: The subjects (28 Cavia cobaya) were divided into control and treatment groups. The control group was left untreated, while the treatment group received a hydroxyapatite scaffold of Portunus pelagicus shell in the tooth socket. The expression of BSP and DMP1 was determined by immunohistochemical staining on days 7 and 14. One-way analysis of variance and Tukey{\textquoteright}s honest significance difference test were used to find the groups with the most significant difference. Results: The highest mean expression of BSP and DMP1 was in the day 14 treatment group, while the lowest was in the day 7 control group. Conclusion: Administering hydroxyapatite scaffold derived from the Portunus pelagicus shell to the post-extraction sockets increased the expression of both BSP and DMP1.",

keywords = "BSP, DMP1, crab shell, hydroxyapatite, medicine",

author = "Kamadjaja, {Michael Josef Kridanto} and Sherman Salim and Waluyo, {Wiwik Herawati} and {Ahmad Noor}, {Tengku Natasha Eleena binti Tengku}",

note = "Publisher Copyright: Copyright {\textcopyright} 2023 Dental Journal (Majalah Kedokteran Gigi)",

year = "2023",

doi = "10.20473/J.DJMKG.V56.I2.P104-108",

language = "English",

volume = "56",

pages = "104--108",

journal = "Dental Journal",

issn = "1978-3728",

number = "2",

}

TY - JOUR

T1 - Evaluation of BSP and DMP1 in hydroxyapatite crab shells used for dental socket preservation

AU - Kamadjaja, Michael Josef Kridanto

AU - Salim, Sherman

AU - Waluyo, Wiwik Herawati

AU - Ahmad Noor, Tengku Natasha Eleena binti Tengku

PY - 2023

Y1 - 2023

N2 - Background: Bone resorption due to tooth extraction leads to unpredictable bone volume for future prosthetics. Crab shells were promoted as a solution to prevent bone resorption, along with an effort to reduce biological waste. Purpose: This study aimed to analyze the expression of bone sialoprotein (BSP) and dentine matrix protein-1 (DMP1) in the wound healing process in tooth-extraction sockets after applying a crab shell-derived hydroxyapatite scaffold. Methods: The subjects (28 Cavia cobaya) were divided into control and treatment groups. The control group was left untreated, while the treatment group received a hydroxyapatite scaffold of Portunus pelagicus shell in the tooth socket. The expression of BSP and DMP1 was determined by immunohistochemical staining on days 7 and 14. One-way analysis of variance and Tukey’s honest significance difference test were used to find the groups with the most significant difference. Results: The highest mean expression of BSP and DMP1 was in the day 14 treatment group, while the lowest was in the day 7 control group. Conclusion: Administering hydroxyapatite scaffold derived from the Portunus pelagicus shell to the post-extraction sockets increased the expression of both BSP and DMP1.

AB - Background: Bone resorption due to tooth extraction leads to unpredictable bone volume for future prosthetics. Crab shells were promoted as a solution to prevent bone resorption, along with an effort to reduce biological waste. Purpose: This study aimed to analyze the expression of bone sialoprotein (BSP) and dentine matrix protein-1 (DMP1) in the wound healing process in tooth-extraction sockets after applying a crab shell-derived hydroxyapatite scaffold. Methods: The subjects (28 Cavia cobaya) were divided into control and treatment groups. The control group was left untreated, while the treatment group received a hydroxyapatite scaffold of Portunus pelagicus shell in the tooth socket. The expression of BSP and DMP1 was determined by immunohistochemical staining on days 7 and 14. One-way analysis of variance and Tukey’s honest significance difference test were used to find the groups with the most significant difference. Results: The highest mean expression of BSP and DMP1 was in the day 14 treatment group, while the lowest was in the day 7 control group. Conclusion: Administering hydroxyapatite scaffold derived from the Portunus pelagicus shell to the post-extraction sockets increased the expression of both BSP and DMP1.

KW - BSP

KW - DMP1

KW - crab shell

KW - hydroxyapatite

KW - medicine

UR - http://www.scopus.com/inward/record.url?scp=85153971217&partnerID=8YFLogxK

U2 - 10.20473/J.DJMKG.V56.I2.P104-108

DO - 10.20473/J.DJMKG.V56.I2.P104-108

M3 - Article

AN - SCOPUS:85153971217

SN - 1978-3728

VL - 56

SP - 104

EP - 108

JO - Dental Journal

JF - Dental Journal

IS - 2

ER -

Evaluation of BSP and DMP1 in hydroxyapatite crab shells used for dental socket preservation

Abstract

Keywords

Access to Document

Fingerprint

Cite this