Ethyl (E)-4-(2,4-dimethoxyphenyl)-6-(2,4-dimethoxystyryl)-2-oxo-1,2,3,4-tetrahydropyrimidine- 5-carboxylate

Hery Suwito, Lutfan Zulianto, Kautsar Ul Haq, Erwanto Erwanto, Abdulloh Abdulloh, Alfinda Novi Kristanti, Indriani Indriani

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

A new compound belonging to the “heterostilbene” derivative, namely ethyl (E)-4-(2,4-dimethoxyphenyl)-6-(2,4-dimethoxystyryl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (2), has been successfully synthesized as an unprecedented side product of the Biginelli reaction between 2,4-dimethoxybenzaldehyde, ethyl acetoacetate and urea, employing PTSA as catalyst in reflux conditions and using ethanol as solvent. The molecular structure of compound (2) was established by FTIR, HRESIMS, 1D and 2D NMR.

Original languageEnglish
Article numberM946
JournalMolBank
Volume2017
Issue number3
DOIs
Publication statusPublished - 1 Sept 2017

Keywords

  • Biginelli reaction
  • Multicomponent reaction
  • Side product

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