TY - JOUR
T1 - Ethyl 5-methyl-7-(4-morpholinophenyl)-4,7-dihydrotetrazolo[1,5-a]pyrimidine-6-carboxylate
AU - Suwito, Hery
AU - Kurnyawaty, Noorma
AU - Ul Haq, Kautsar
AU - Abdulloh, Abdulloh
AU - Indriani, Indriani
N1 - Publisher Copyright:
© 2018 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2018/6
Y1 - 2018/6
N2 - A new compound belonging to a dihydrotetrazolopyrimidine derivative, that is, ethyl 5-methyl-7-(4-morpholinophenyl)-4,7-dihydrotetrazolo[1,5-a]pyrimidine-6-carboxylate, was successfully synthesized using a Biginelli reaction between 4-morpholinobenzaldehyde, ethyl acetoacetate, and 5-aminotetrazole with p-toluenesulfonic acid (pTSA) as a catalyst in ethanol under reflux. The molecular structure of the title compound was characterized on the basis of spectroscopic evidence, using FTIR, HRESI-MS, 1H- and 13C-NMR, and 2D NMR.
AB - A new compound belonging to a dihydrotetrazolopyrimidine derivative, that is, ethyl 5-methyl-7-(4-morpholinophenyl)-4,7-dihydrotetrazolo[1,5-a]pyrimidine-6-carboxylate, was successfully synthesized using a Biginelli reaction between 4-morpholinobenzaldehyde, ethyl acetoacetate, and 5-aminotetrazole with p-toluenesulfonic acid (pTSA) as a catalyst in ethanol under reflux. The molecular structure of the title compound was characterized on the basis of spectroscopic evidence, using FTIR, HRESI-MS, 1H- and 13C-NMR, and 2D NMR.
KW - Biginelli reaction
KW - Dihydrotetrazolopyrimidine derivative
KW - Multicomponent reaction
UR - http://www.scopus.com/inward/record.url?scp=85049535318&partnerID=8YFLogxK
U2 - 10.3390/M998
DO - 10.3390/M998
M3 - Article
AN - SCOPUS:85049535318
SN - 1422-8599
VL - 2018
JO - MolBank
JF - MolBank
IS - 2
M1 - M998
ER -