Electrochemical detection of ciprofloxacin using Cu-Ag core-shell nanoparticles modified screen-printed electrode

Laurencia Gabrielle Sutanto, Prastika Krisma Jiwanti

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

A new sensitive, efficient, and cheap electrochemical sensor for ciprofloxacin detection was developed. Simple chemical reduction was used to synthesize Cu-Ag core-shell nanoparticles (Cu@Ag NPs). Cu@Ag NPs were characterized using UV-vis then modified onto screen-printed electrode (SPE) surface by the drop-casting method. Square-wave voltammetry (SWV) was used to study the response of ciprofloxacin towards the modified electrode. Electrochemical measurements were carried out using phosphate buffer solution pH 7. Under optimized experimental conditions, the developed electrodes exhibited a linear range of 30-100 μM. The Cu@Ag/SPE has good sensitivity with a low detection limit of 0.213 μM. Analysis on real samples tested in artificial urine. The recovery of the analyte in the real sample was 98.82%. This shows that the developed electrode can be used for fast, easy, and sensitive detection of ciprofloxacin in urine samples.

Original languageEnglish
Title of host publication2023 IEEE International Conference on Sensors and Nanotechnology, SENNANO 2023
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages166-168
Number of pages3
ISBN (Electronic)9798350333312
DOIs
Publication statusPublished - 2023
Event2023 IEEE International Conference on Sensors and Nanotechnology, SENNANO 2023 - Putrajaya, Malaysia
Duration: 26 Sept 202327 Sept 2023

Publication series

Name2023 IEEE International Conference on Sensors and Nanotechnology, SENNANO 2023

Conference

Conference2023 IEEE International Conference on Sensors and Nanotechnology, SENNANO 2023
Country/TerritoryMalaysia
CityPutrajaya
Period26/09/2327/09/23

Keywords

  • ciprofloxacin
  • Cu@Ag
  • electrochemical detection
  • SPE

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