TY - JOUR
T1 - Efficacy of Vitamin C and E on the Level of Antioxidative Stress and Steroid Hormones in Albino Rats with Environmental Stress
AU - Dewi, Winda Kusuma
AU - Fikri, Faisal
AU - Purnomo, Agus
AU - Chhetri, Shekhar
AU - Maslamama, Salipudin Tasil
AU - Purnama, Muhammad Thohawi Elziyad
N1 - Publisher Copyright:
© 2023 Indian Veterinary Assocaition. All rights reserved.
PY - 2023/1
Y1 - 2023/1
N2 - The aim of this study was to evaluate the efficacy of vitamin C and E in albino rats exposed with environmental stress on the following variables i.e. superoxide dismutase, malondialdehyde, catalase, testosterone, and cortisol level. A total of 20 albino rats were assigned into four treatment groups i.e. (C) normal saline, (T1) vitamin C and E, (T2) induced with stress, (T3) induced with stress and vitamin C and E. All groups were maintained for 4 weeks, respectively. Serum samples were collected from 5 ml of blood, respectively then evaluated using enzymol method for level of antioxidative stress and ELISA method for steroid hormone determination.In result, T3 group improved significantly difference compared to T2 group in the variable of malondialdehyde, catalase, testosterone, and cortisol. Meanwhile, there was no significant difference in the superoxide dismutase level between T3 and T2groups. In conclusion, vitamin C and E had an efficacy to ameliorate albino rats condition exposed with environmental stress.
AB - The aim of this study was to evaluate the efficacy of vitamin C and E in albino rats exposed with environmental stress on the following variables i.e. superoxide dismutase, malondialdehyde, catalase, testosterone, and cortisol level. A total of 20 albino rats were assigned into four treatment groups i.e. (C) normal saline, (T1) vitamin C and E, (T2) induced with stress, (T3) induced with stress and vitamin C and E. All groups were maintained for 4 weeks, respectively. Serum samples were collected from 5 ml of blood, respectively then evaluated using enzymol method for level of antioxidative stress and ELISA method for steroid hormone determination.In result, T3 group improved significantly difference compared to T2 group in the variable of malondialdehyde, catalase, testosterone, and cortisol. Meanwhile, there was no significant difference in the superoxide dismutase level between T3 and T2groups. In conclusion, vitamin C and E had an efficacy to ameliorate albino rats condition exposed with environmental stress.
KW - environmental stress
KW - oxidative stress
KW - steroid hormone
KW - vitamin C
KW - vitamin E
UR - http://www.scopus.com/inward/record.url?scp=85154594761&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:85154594761
SN - 0019-6479
VL - 100
SP - 16
EP - 19
JO - Indian Veterinary Journal
JF - Indian Veterinary Journal
IS - 1
ER -