Drug is a substance that when it consumed will directly affect the body, especially the central nervous system of the brain so that when it is improperly used then physical, psychological, and social functioning disorders will occur. The rehabilitation process is a way to stop the use of drugs with various therapeutic methods suchas methadone therapy. The experiment was carried out with 8 men subjects who were addicted, but were in the rehabilitation stage. The EEG recording was carried out for 5 minutes with two stages, namely before and after using methadone and with two conditions: open and closed eyes. From the experimental results it was found that an increase in alpha and theta wave activity in closed eye conditions and an increase in alpha and a decrease in theta wave activity in open eye conditions are obtained.