Effects of Curcumin on Inflammatory Response During Exercise-Induced Muscle Damage (Literature Review)

Novadri Ayubi, Nining Widyah Kusnanik, Lilik Herawati, Anton Komaini, Toho Cholik Mutohir, Andri Gemaini, Ardi Setyo Nugroho, Nuridin Widya Pranoto

Research output: Contribution to journalReview articlepeer-review

10 Citations (Scopus)


This study aimed to evaluate the effect of curcumin on the inflammatory response during exercise-induced muscle damage (EIMD) is a literature review. The method applied to this article was a comprehensive strategy such as searching for articles in research journal databases. The databases were taken from Pubmed/MEDLINE, Scopus, Web of Science, and Embase. The keywords were curcumin, inflammation, Exercise-Induced Muscle Damage, Sport, Exercise, and Healthy Lifestyle. There were 30 articles obtained, and 10 articles were analyzed through the purpose, suitability of the topic, sample size, research protocol, and the results of each article. The results of this study explain that curcumin was able to provide anti-inflammatory effects by reducing pro-inflammatory cytokines such as IL-6, IL-8, TNF-α. Curcumin can also reduce muscle pain intensity, decrease CK activity, and increase ROM. The curcumin dose (>180 mg/day) showed to reduce various inflammatory responses due to EIMD. Therefore, it is recommended that curcumin be used in individuals who carry out physical activities, leading to muscle damage and inflammation.

Original languageEnglish
Article number146
JournalBiointerface Research in Applied Chemistry
Issue number2
Publication statusPublished - 15 Apr 2023


  • Curcumin
  • Exercise
  • Exercise-Induced Muscle Damage
  • Healthy Lifestyle
  • Sport


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