Candida albicans is a yeast that commensally inhabits the oral cavity might cause opportunistic infections and become pathogen in immunesupressed condition. More than 90% oral candidiasis caused by C. albicans infections. Citrus limon peel has active compound that may inhibits C. albicans growth. The purpose of this study is to investigate in vitro effectivness concentration of Citrus limon peel oil on C. albicans growth. Citrus limon peel essential oil that has obtained the serial dilution concentrations of 25%, 12.5%, 6.25%, 3.125%, 1.56%, 0.78%, 0.39% and 0.195% and added Candida albicans that had been grown in Sabouraud broth media. Furthermore, C.albicans grown on Sabouraud Dextrose Agar and colonies were counted. MIC (Minimum Inhibitory Concentration) Citrus limon peel essential oil was 0.78%. MFC (Minimum Fungicidal Concentration) Citrus lemon peel essential oil 1.56%. Citrus limon peel essential oil with concentration 25%, 12.5%, 6.25%, 3.125% and 1.56% had in vitro effectiveness inhibiting and cause C. albicans death and Citrus limon peel esential oil with concentration 0.78% had in vitro effectiveness inhibiting C. albicans growth.

Original languageEnglish
Pages (from-to)2957-2961
Number of pages5
JournalBiochemical and Cellular Archives
Publication statusPublished - 2020


  • Antifungal
  • Candida albicans
  • Citrus limon peel
  • Essential oil
  • Medicine


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