TY - JOUR
T1 - Effect of transcutaneous auricular vagus nerve stimulation in addition to exercises on disability in chronic low back pain patients
T2 - a randomized controlled study
AU - Uzlifatin, Yaniar
AU - Arfianti, Lydia
AU - Wardhani, Indrayuni Lukitra
AU - Hidayati, Hanik Badriyah
AU - Melaniani, Soenarnatalina
N1 - Funding Information:
This study was supported by Medical Rehabilitation Installation, Dr. Soetomo Hospital Surabaya, Indonesia.
Publisher Copyright:
© 2023 Faculty of Anaesthesia, Pain and Intensive Care, AFMS. All rights reserved.
PY - 2023/2/1
Y1 - 2023/2/1
N2 - Background & objective: Low back pain is a common problem, especially in the young and middle-aged working people, and is often very resistant to the conventional management. We evaluated the impact of transcutaneous auricular vagus nerve stimulation (tVNS), applied in conjunction with an exercise treatment program, on disability in chronic low back pain patients. Methodology: The study was conducted from June to October 2022. Twenty-two patients aged 42.18 ± 9.91 y, with Numerical Pain Rating Scale (NPRS) score 5.64 ± 1.09 and Roland Morris Disability Questionnaire (RMDQ) score 10 ± 4.670, were randomly assigned to two groups. The control group received only exercise therapy (EXC group, n = 11), and the intervention group received exercise and tVNS therapy (EXC + tVNS group, n = 11). The primary outcome was RMDQ, measured before and after the intervention. Result: The mean RMDQ was significantly improved in both groups. In the intervention group the improvement was from 9.45 ± 4.44 to 2.18 ± 2.71 (P = 0.000), in the control group it was from 10.55 ± 5.05 to 2.36 ± 2.06 (P = 0.001). Inter-group comparison showed no significant difference. The effect size of the control group (2.12) was similar with the intervention group (1.98). Conclusion: Addition of 2-weeks tVNS to exercise therapy did not show superior effect on disability improvement compared to exercise only in chronic low back pain. Exercise alone was sufficient to improve the mean RMDQ.
AB - Background & objective: Low back pain is a common problem, especially in the young and middle-aged working people, and is often very resistant to the conventional management. We evaluated the impact of transcutaneous auricular vagus nerve stimulation (tVNS), applied in conjunction with an exercise treatment program, on disability in chronic low back pain patients. Methodology: The study was conducted from June to October 2022. Twenty-two patients aged 42.18 ± 9.91 y, with Numerical Pain Rating Scale (NPRS) score 5.64 ± 1.09 and Roland Morris Disability Questionnaire (RMDQ) score 10 ± 4.670, were randomly assigned to two groups. The control group received only exercise therapy (EXC group, n = 11), and the intervention group received exercise and tVNS therapy (EXC + tVNS group, n = 11). The primary outcome was RMDQ, measured before and after the intervention. Result: The mean RMDQ was significantly improved in both groups. In the intervention group the improvement was from 9.45 ± 4.44 to 2.18 ± 2.71 (P = 0.000), in the control group it was from 10.55 ± 5.05 to 2.36 ± 2.06 (P = 0.001). Inter-group comparison showed no significant difference. The effect size of the control group (2.12) was similar with the intervention group (1.98). Conclusion: Addition of 2-weeks tVNS to exercise therapy did not show superior effect on disability improvement compared to exercise only in chronic low back pain. Exercise alone was sufficient to improve the mean RMDQ.
KW - Chronic low back pain
KW - Disability
KW - Exercise
KW - Transcutaneous Auricular Vagus Nerve Stimulation
UR - http://www.scopus.com/inward/record.url?scp=85149258027&partnerID=8YFLogxK
U2 - 10.35975/apic.v27i1.2084
DO - 10.35975/apic.v27i1.2084
M3 - Article
AN - SCOPUS:85149258027
SN - 1607-8322
VL - 27
SP - 73
EP - 81
JO - Anaesthesia, Pain and Intensive Care
JF - Anaesthesia, Pain and Intensive Care
IS - 1
ER -