Effect of socioeconomic status on lung cancer survival: A mediation analysis based on Bayesian network approach

Kartika Nur Anisa, Shi Woei Lin

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Identifying factors and mechanisms that influence survival time of cancer patients is critical for healthcare decision makers. Besides the medical conditions, socioeconomic status (SES) of a patient may also significantly affect the prognosis of the disease. This study aims to investigate key determinants that affect lung cancer survival and to evaluate the direct and indirect effects (via other mediating variables) of SES on survival time. Bayesian Networks (BNs) were proposed and implemented to analyze a large database from The Surveillance, Epidemiology, and End Results (SEER) of the National Cancer Institute of the United States. Results show that the cancer stage at diagnosis is the most critical factor for determining survival time. Investigation of the underlying mechanism identifies both direct and indirect effects of SES on survival time, but the mediation analysis also indicates that the disparity on timely diagnosis (i.e., stage at diagnosis) caused by SES is only marginally significant.

Original languageEnglish
Title of host publication2017 IEEE International Conference on Industrial Engineering and Engineering Management, IEEM 2017
PublisherIEEE Computer Society
Pages1500-1504
Number of pages5
ISBN (Electronic)9781538609484
DOIs
Publication statusPublished - 2 Jul 2017
Externally publishedYes
Event2017 IEEE International Conference on Industrial Engineering and Engineering Management, IEEM 2017 - Singapore, Singapore
Duration: 10 Dec 201713 Dec 2017

Publication series

NameIEEE International Conference on Industrial Engineering and Engineering Management
Volume2017-December
ISSN (Print)2157-3611
ISSN (Electronic)2157-362X

Conference

Conference2017 IEEE International Conference on Industrial Engineering and Engineering Management, IEEM 2017
Country/TerritorySingapore
CitySingapore
Period10/12/1713/12/17

Keywords

  • Bayesian Networks
  • Lung Cancer
  • Socioeconomic Status (SES)
  • Survival Months

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