TY - JOUR
T1 - Effect of Sapodilla (ManilkarazapotaL.) Leaves Extract on Pancreasof Alloxan Induced Mice
T2 - A Histopathological Study
AU - Septiani, Mela
AU - Solikhah, Tridiganita Intan
AU - Setiawan, Boedi
N1 - Publisher Copyright:
© 2024 Indian Veterinary Assocaition. All rights reserved.
PY - 2024/5
Y1 - 2024/5
N2 - Diabetes mellitusis a metabolic disorder in the form of high levels of glucose in the blood. This study was conducted to determine the effect of Manilkara zapota leaf extract (MZLE) on alloxan-induced mice. 25 male mice ± 3 months, 25-35 g, treated with P1 (MZLE 140 mg/kg), P2 (MZLE 70mg/kg), K+ (Pioglitazone 20 mg/kg), P0 (normal control) and K- (diabetescontrol). Pancreas was taken on day 14 after being given therapy. Data analysis by Kruskal Wallis and MannWhitney. MZLE 140 mg/kg showed that the highest pancreatic protection compared to MZLE 70 mg/kg and pioglitazone 20 mg/kg.
AB - Diabetes mellitusis a metabolic disorder in the form of high levels of glucose in the blood. This study was conducted to determine the effect of Manilkara zapota leaf extract (MZLE) on alloxan-induced mice. 25 male mice ± 3 months, 25-35 g, treated with P1 (MZLE 140 mg/kg), P2 (MZLE 70mg/kg), K+ (Pioglitazone 20 mg/kg), P0 (normal control) and K- (diabetescontrol). Pancreas was taken on day 14 after being given therapy. Data analysis by Kruskal Wallis and MannWhitney. MZLE 140 mg/kg showed that the highest pancreatic protection compared to MZLE 70 mg/kg and pioglitazone 20 mg/kg.
KW - Diabetes
KW - Histopathology
KW - Manilkara zapota
UR - http://www.scopus.com/inward/record.url?scp=85194954904&partnerID=8YFLogxK
U2 - 10.62757/IVA.2024.101.5.15-18
DO - 10.62757/IVA.2024.101.5.15-18
M3 - Article
AN - SCOPUS:85194954904
SN - 0019-6479
VL - 101
SP - 15
EP - 18
JO - Indian Veterinary Journal
JF - Indian Veterinary Journal
IS - 5
ER -