TY - GEN
T1 - Effect of Methadone on the Brain Activity in Close Eyes Condition
AU - Turnip, Arjon
AU - Kusumandari, Dwi Esti
AU - Sobana, Siti Aminah
AU - Istiqomah, Arifah Nur
AU - Hidayat, Teddy
AU - Iskandar, Shelly
AU - Nabila, Yumna
AU - Amrina, Ririn
AU - Madona, Putri
N1 - Funding Information:
Acknowledgements This research was supported by Technical Implementation Unit for Instrumentation Development, Indonesian Institute of Sciences and funded by RISTEKDIKTI by INSINAS 2019, Indonesia.
Publisher Copyright:
© 2021, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
PY - 2021
Y1 - 2021
N2 - Drug abuse in various parts of the world is increasingly widespread. Therefore, a drug addict should immediately stop and must be recovered. To overcome the symptoms of addiction, the use of methadone as a synthetic drug to replace opioid type drugs is recommended. In this paper, an experiment with rehabilitation patients to identify the effect of the drugs on the brain activity in the frontal, central, temporal, and occipital lobes is proposed. The EEG data collection is performed using 18 channel electrodes, namely central: C3, C4; frontal: Fp1, Fp2, F3, F2, F4, F7, F8; occipital: P3, Pz, P4, O1, O2; and temporal: T3, T4, T5, T6. In the brain signals record, subjects were asked to comfortably sit in a chair. The recording was done in three sessions: 5 min before drinking methadone, 10 and 60 min after drinking the methadone, respectively. To reduce background noise and artifacts removal, bandpass filter (0.5–50 Hz) and wavelet method were applied, respectively. From this experiment, it was found that a decrease in amplitude after methadone intake for average in four lobes is obtained. The result indicates that the use of methadone is highly effected on the entire brainwave activity which indicates a decrease in the level of desire to do activities.
AB - Drug abuse in various parts of the world is increasingly widespread. Therefore, a drug addict should immediately stop and must be recovered. To overcome the symptoms of addiction, the use of methadone as a synthetic drug to replace opioid type drugs is recommended. In this paper, an experiment with rehabilitation patients to identify the effect of the drugs on the brain activity in the frontal, central, temporal, and occipital lobes is proposed. The EEG data collection is performed using 18 channel electrodes, namely central: C3, C4; frontal: Fp1, Fp2, F3, F2, F4, F7, F8; occipital: P3, Pz, P4, O1, O2; and temporal: T3, T4, T5, T6. In the brain signals record, subjects were asked to comfortably sit in a chair. The recording was done in three sessions: 5 min before drinking methadone, 10 and 60 min after drinking the methadone, respectively. To reduce background noise and artifacts removal, bandpass filter (0.5–50 Hz) and wavelet method were applied, respectively. From this experiment, it was found that a decrease in amplitude after methadone intake for average in four lobes is obtained. The result indicates that the use of methadone is highly effected on the entire brainwave activity which indicates a decrease in the level of desire to do activities.
KW - Brain activity
KW - EEG-P300
KW - Frontal lobe
KW - Methadone
KW - Visual stimuli
UR - http://www.scopus.com/inward/record.url?scp=85104739889&partnerID=8YFLogxK
U2 - 10.1007/978-981-33-4062-6_14
DO - 10.1007/978-981-33-4062-6_14
M3 - Conference contribution
AN - SCOPUS:85104739889
SN - 9789813340619
T3 - Advances in Intelligent Systems and Computing
SP - 157
EP - 168
BT - Cyber Physical, Computer and Automation System - A Study of New Technologies
A2 - Joelianto, Endra
A2 - Turnip, Arjon
A2 - Widyotriatmo, Augie
PB - Springer Science and Business Media Deutschland GmbH
T2 - International Conference on Cyber Physical, Computer and Automation Systems, CPCAS 2019
Y2 - 13 November 2019 through 15 November 2019
ER -
