The aimed was associated to effect of HDM immunotherapy in children with chronic sinusitis due to HDM allergies. Participants were divided into 2 groups, consisting of treatment group (immunotherapy) with 23 patients, and control group with 22 patients. Treatment groups received HDM immunotherapy for 14 weeks. The statistical analysis used McNemar and Chi-Square test with 95% confidence interval (CI) and p <0.05. There was a significant difference in the improvement of Waters’ view in the treatment and control groups (p <0.001). There were significant differences in the absence of itchy nose symptom (p = 0.003), colored secretion (p = 0.024), itchy eyes (p = 0.019), wheezing (p = 0.024), shortness of breath (p = 0.039), sneezing (p <0.001), postnasal drip (p <0.001), stuffy nose (p <0.001), snoring (p <0.001), cough (p <0.001), phlegm (p <0.001), and rhinorrhea (p <0.001). There is an improvement in pediatric chronic sinusitis before and after HDM immunotherapy.

Original languageEnglish
Pages (from-to)1651-1658
Number of pages8
JournalJournal of International Dental and Medical Research
Issue number4
Publication statusPublished - 2020


  • Immunotherapy
  • chronic sinusitis
  • house dust mites
  • pediatric


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